Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

407
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
407
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

1.9K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
1.9K
Imaging Studies V: Intravenous Urography and Retrograde Pyelography01:22

Imaging Studies V: Intravenous Urography and Retrograde Pyelography

858
IntroductionIntravenous Urography (IVU) and Retrograde Pyelography (RP) are important diagnostic imaging techniques used to evaluate the urinary system. These methods help identify structural abnormalities, obstructions, and functional issues in the kidneys, ureters, and bladder. Both procedures use iodine-based contrast media to enhance the visibility of urinary tract structures on X-ray images, though they differ in their methods and indications.1. Intravenous Urography (IVU)Intravenous...
858
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

723
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
723
Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

227
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
227
Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

966
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
966

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Leveraging Real-World Evidence to Inform Regulatory, Clinical, and Coverage Decisions Related to Glucagon-Like Peptide-1-Based Therapies: Synopsis of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.

Annals of internal medicine·2026
Same author

Shaping antibiotic resistance gene fate in soil-plant systems: Dual roles of biochar physicochemical traits mediated by pyrolysis conditions.

Environmental research·2026
Same author

Impact of Prenatal Cell-Free DNA Screening on Sex Chromosome Aneuploidy Diagnoses in Infants and Children.

Prenatal diagnosis·2026
Same author

Microplastics enhance the enrichment and dissemination of antibiotic resistance genes in aquatic environments: A meta-analysis.

Journal of environmental sciences (China)·2026
Same author

Breaking the sequential treatment paradigm: Plasma-assisted electrosorption enables one-step algal cell demolition, P recovery, and N stripping from eutrophic waters.

Water research·2026
Same author

Degradation of sulfamethoxazole in high-salinity wastewater by low-temperature plasma: efficiency, mechanism, and toxicity assessment.

Journal of environmental management·2026

Related Experiment Video

Updated: Dec 30, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

753

Cost-effectiveness of Imaging Protocols for Suspected Appendicitis.

Rebecca Jennings1,2, He Guo3, Adam Goldin4

  • 1Departments of Pediatrics and rebecca.jennings@seattlechildrens.org.

Pediatrics
|January 23, 2020
PubMed
Summary

For suspected appendicitis, using ultrasound first, followed by CT if needed, is the most cost-effective imaging strategy for moderate-risk patients. Tailored imaging based on appendicitis risk optimizes outcomes and reduces costs.

More Related Videos

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.1K
Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta
07:12

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta

Published on: September 8, 2023

4.0K

Related Experiment Videos

Last Updated: Dec 30, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

753
Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.1K
Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta
07:12

Author Spotlight: Using Point-of-Care Ultrasound for Comprehensive Evaluation of the Abdominal Aorta

Published on: September 8, 2023

4.0K

Area of Science:

  • Medical Imaging
  • Health Economics
  • Diagnostic Accuracy

Background:

  • Inaccurate appendicitis diagnosis increases healthcare costs and patient morbidity.
  • Ultrasound is cheaper than CT/MRI but has lower sensitivity and may not visualize the appendix.

Purpose of the Study:

  • To determine the most cost-effective imaging strategy for suspected appendicitis.
  • To compare 10 different imaging approaches using a decision-analytic model.

Main Methods:

  • A cost-effectiveness analysis was performed using a decision-analytic model.
  • Data on quality-of-life and costs were sourced from published literature and secondary data.
  • Sensitivity analyses explored variations in appendicitis risk and ultrasound visualization rates.

Main Results:

  • The optimal strategy for moderate-risk patients involves initial ultrasound, followed by CT if the appendix isn't visualized but secondary signs of inflammation are present ($4815.03 cost; 0.99694 QALYs).
  • Other strategies exceeded standard willingness-to-pay thresholds or were less effective and more costly.
  • Cost-effectiveness was significantly influenced by patient risk for appendicitis, but not by ultrasound visualization rates.

Conclusions:

  • Tailored imaging strategies based on individual appendicitis risk are most cost-effective.
  • Imaging is not cost-effective for patients with appendicitis probability below 16% or above 95%.
  • For moderate-risk patients, ultrasound is sufficient even without visualizing the appendix, provided secondary signs of inflammation are absent.