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Developing an Executive Functioning Composite Score for Research and Clinical Trials.

Grant L Iverson1, Justin E Karr1, Douglas P Terry1

  • 1Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Spaulding Research Institute, and Home Base, A Red Sox Foundation and Massachusetts General Hospital Program, Boston, MA 02129, USA.

Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists
|January 23, 2020
PubMed
Summary
This summary is machine-generated.

Developing a single composite score for executive functioning (EF) using the Delis-Kaplan Executive Function System (D-KEFS) is crucial for research. This study found that while composite scores correlate with IQ, some appear redundant, necessitating further validation.

Keywords:
AssessmentExecutive functionsNorms/normative studies

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Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Psychometrics

Background:

  • Executive functioning (EF) involves complex cognitive processes essential for goal-directed behavior.
  • Current assessment of EF typically relies on multiple tests, yielding numerous scores, complicating interpretation.
  • A unified composite score for EF would enhance research and clinical trial efficiency.

Purpose of the Study:

  • To examine candidate composite scores for executive functioning derived from the Delis-Kaplan Executive Function System (D-KEFS).
  • To evaluate the psychometric properties and association with intelligence (IQ) of these composite scores.
  • To identify potential redundancies among composite scores for streamlined assessment.

Main Methods:

  • Utilized data from 875 adults (ages 20-89) in the D-KEFS standardization sample.
  • Formed eight composite scores from seven Total Achievement scores across three D-KEFS tests (Trail Making, Verbal Fluency, Color-Word Interference).
  • Compared composite scores based on psychometric properties and correlation with IQ.

Main Results:

  • Composite score distributions exhibited mild to severe skewness, with some showing ceiling effects.
  • All composite scores demonstrated a medium positive correlation with IQ.
  • High intercorrelations were observed among composite scores, suggesting redundancy in some measures.

Conclusions:

  • The study contributes to developing a robust cognitive endpoint for research and clinical trials.
  • Further research is required to confirm the reliability and ecological validity of the proposed composite EF scores.
  • Findings suggest potential for a more concise EF assessment within research settings.