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Peritoneal clearances. Long-term study.

D A Procaccini1, M Querques, A Tappi

  • 1Division of Nephrology, Regional Hospital, Foggia, Italy.

ASAIO Transactions
|July 1, 1988
PubMed
Summary
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Continuous ambulatory peritoneal dialysis (CAPD) demonstrates stable peritoneal membrane permeability over extended periods. Factors like patient age, diabetes, or peritonitis episodes do not significantly impact solute clearance, indicating CAPD

Area of Science:

  • Nephrology
  • Biomedical Engineering

Background:

  • Continuous ambulatory peritoneal dialysis (CAPD) is a crucial treatment for end-stage renal disease.
  • Understanding factors influencing peritoneal membrane permeability is vital for optimizing dialysis efficacy.

Purpose of the Study:

  • To assess the impact of patient age, duration of CAPD, peritonitis episodes, and diabetes on peritoneal membrane permeability.
  • To evaluate the long-term stability of peritoneal clearances (PC) in patients undergoing CAPD.

Main Methods:

  • A prospective study involving 51 long-term CAPD patients (8 diabetic).
  • Peritoneal clearances (PC) were measured prospectively every 6 months.
  • Data analyzed based on patient demographics, time on CAPD, peritonitis history, and diabetic status.

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Main Results:

  • Patient age and diabetic status did not significantly affect PC.
  • Positive correlations were observed between PC of creatinine, uric acid, and phosphate with increased time on CAPD.
  • Peritonitis episodes did not significantly alter PC, even with more than three episodes.

Conclusions:

  • Long-term CAPD maintains stable peritoneal membrane permeability for small solute removal.
  • CAPD can provide effective dialysis over extended durations, irrespective of common influencing factors.