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Related Concept Videos

The Parathyroid Glands00:59

The Parathyroid Glands

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The two pairs of parathyroid glands embedded within the posterior surface of the thyroid gland are restricted by a dense capsule around them. These glands comprise two distinct cell populations—parathyroid oxyphil and parathyroid principal cells- pivotal in calcium homeostasis.
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by...
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Related Experiment Video

Updated: Dec 30, 2025

Intracarotid Cancer Cell Injection to Produce Mouse Models of Brain Metastasis
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Parotid metastases from thyroid carcinomas.

Zhi-Hong Wu1, Ming-Hua Ge2,3, Jun Cao3

  • 1Wenzhou Medical University-Affiliated Yiwu Central Hospital Yiwu, Zhejiang, China.

International Journal of Clinical and Experimental Pathology
|January 23, 2020
PubMed
Summary

Parotid metastases from thyroid carcinoma are rare, occurring in 0.019% of cases. Early detection and multidisciplinary communication are crucial for managing these rare thyroid cancer presentations.

Keywords:
Thyroid carcinomahistologic subtypeparotid metastasistreatment

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Area of Science:

  • Oncology
  • Head and Neck Surgery

Background:

  • Parotid metastases (PMs) from thyroid carcinoma (TC) are exceptionally rare.
  • Diagnostic and management strategies for PMs from TC require further elucidation.

Purpose of the Study:

  • To investigate the incidence, characteristics, and management of parotid gland metastases originating from thyroid carcinoma.
  • To emphasize the importance of interdisciplinary communication in diagnosing rare metastatic cases.

Main Methods:

  • Retrospective analysis of three patients with TC and PM from institutional databases (1996-2015).
  • Comprehensive literature review of PM from TC using PubMed, Embase, and ISI Web of Science (1996-2015).

Main Results:

  • Identified only three cases (0.019%) of PM in a cohort of 15,780 TC patients.
  • Reviewed patient characteristics, histological findings, treatments, and outcomes for these rare cases.
  • Synthesized findings from a literature search of similar rare occurrences.

Conclusions:

  • Thyroid carcinoma presenting as parotid metastasis is a rare clinical entity.
  • Close collaboration among clinicians, radiologists, and histopathologists is essential for accurate diagnosis and management.
  • Highlights the need for vigilance in identifying rare metastatic patterns of thyroid cancer.