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An Intestine/Liver Microphysiological System for Drug Pharmacokinetic and Toxicological Assessment
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Application of microphysiological systems in biopharmaceutical research and development

Norman C Peterson1, Prathap Kumar Mahalingaiah2, Aaron Fullerton3

  • 1Clinical Pharmacology and Safety Sciences, AstraZeneca, One Medimmune Way, Gaithersburg, MD 20878, USA. ncpdvmphd@gmail.com.

Lab on a Chip
|January 23, 2020
PubMed
Summary

Tissue microphysiological systems (MPS) mimic in vivo conditions for drug testing. This review highlights advances and challenges in applying MPS for biopharmaceutical preclinical research.

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