Decision by injection without infection
Miwa Sasai1,2, Masahiro Yamamoto1,2
1Department of Immunoparasitology, Research Institute for Microbial Diseases, Osaka University, Suita, Japan.
The Journal of Experimental Medicine
|January 23, 2020
Abstract:
The protozoan pathogen Toxoplasma gondii co-opts host immunity by secreting various effector proteins into host cells. In this issue of JEM, Chen et al. (https://doi.org/10.1084/jem.20181757) report that T. gondii injects an effector called ROP16 without invasion to polarize macrophages toward M2 cells.


