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Intravital-microscopic observations on the intravascular behavior of blood cell components during dietary-induced
M Asano1, C Ohkubo, A Hirokawa
1Department of Physiological Hygiene, Institute of Public Health, Tokyo, Japan.
Biorheology
|January 1, 1988
Abstract:
In normal male rabbits loaded dietary cholesterol, intravital-microscopy revealed a marked acceleration of intravascular adhesiveness of white blood cells and aggregability of red blood cells and a swarming of lipid-laden macrophages in connective tissue space concurrently with a systemic hyperlipidemia and anemia. Possible roles of the microcirculatory changes in the atherogenesis were discussed.