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Updated: Dec 30, 2025

Designing Porous Silicon Films as Carriers of Nerve Growth Factor
Published on: January 25, 2019
[Alzheimer's disease and nerve growth factor gene therapy]
Zhonghua Huang1, Jian Li2, Jun Zhou3
1Department of Neurology, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Abstract:
Gene therapy plays an important role in Alzheimer's disease (AD). In recent years, the research on gene delivery vector has gradually transferred from adenovirus vector, adeno-associated virus vector and lentivirus vector to liposomes and nanomaterial carrier systems. Graphene, the newest member of nanomaterial carrier system, has attracted extensive attention for its well permeability and biocompatibility. The methods of gene therapy can be divided into direct and indirect method. The stem cell therapy, which is the most-well studied one, belongs to the indirect method. In the gene therapy of AD, the selection of appropriate carrier and method will determine the therapeutic effect.
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