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Updated: Dec 30, 2025
An Orthotopic Bladder Tumor Model and the Evaluation of Intravesical saRNA Treatment
Published on: July 28, 2012
Unusual presentation of bladder neuroblastoma in a child: A case report
Jia-Bin Cai1, Jin-Hu Wang2, Min He1
1Division of Surgical Oncology, Department of Pediatric Surgery, Children's Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, Hangzhou 310053, Zhejiang Province, China.
Background:
Neuroblastoma is an extracranial malignant tumor in children that is most often located in the adrenal gland and sympathetic ganglion. Here, we present a rare case of neuroblastoma originating from the urinary bladder.
Case Summary:
A 3-year-old girl presented with lower abdominal pain with micturition. Ultrasound revealed a lower abdominal mass. Abdominal computed tomography scan displayed a solitary mass at the top of the urinary bladder. Blood levels of neuron-specific enolase and lactate dehydrogenase were elevated. We treated the child with partial cystectomy and six courses of chemotherapy, and the outcome at 4-year follow-up was unremarkable.
Conclusion:
Neuroblastoma should be considered when tumors are located in the urinary bladder, especially in the dome; although this presentation is rare, the prognosis is very good.
