Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A computerized approach to closing volume determination.

W O Cramer, W C Miller

    Annals of Allergy
    |January 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A national strategy for a canadian limb loss and limb difference registry.

    Canadian prosthetics & orthotics journal·2026
    Same author

    Influence of insurance type on healthcare utilization among rural people who use drugs.

    Drug and alcohol dependence·2025
    Same author

    Detecting Changes in Comfort, Pain, and Mobility Over Clinical Milestones for Individuals With Lower Limb Loss.

    Canadian prosthetics & orthotics journal·2024
    Same author

    Predicting high quality of participation in adaptive snow-sports for individuals with disabilities: An exploratory study.

    Psychology of sport and exercise·2023
    Same author

    A Mixed-methods Study on Prosthesis Use Among Older Canadians With Lower-limb Amputations.

    Canadian prosthetics & orthotics journal·2023
    Same author

    Protocol for a randomized controlled trial to assess the effect of Self-Management for Amputee Rehabilitation using Technology (SMART): An online self-management program for individuals with lower limb loss.

    PloS one·2023
    Same journal

    Hay fever; a review of the literature for 1945.

    Annals of allergy·2010
    Same journal

    Nasal and sputum smears.

    Annals of allergy·2010
    Same journal

    Determination of penicillin-susceptible strains of bacteria.

    Annals of allergy·2010
    Same journal

    Fleabite reactions; clinical and experimental observations and effect of histamine-azoprotein therapy.

    Annals of allergy·2010
    Same journal

    D.H.E. 45 (dihydroergotamine) in the treatment of allergic megraine.

    Annals of allergy·2010
    Same journal

    Antigenicity of proteins in relation to allergy.

    Annals of allergy·2010
    See all related articles

    A new computer program accurately calculates closing volume from single-breath nitrogen tests. This method offers a reliable, timesaving alternative to visual analysis, reducing observer variability in pulmonary function testing.

    Area of Science:

    • Pulmonary Physiology
    • Medical Imaging & Instrumentation

    Background:

    • The single-breath nitrogen (SB N2) test is a standard method for assessing lung function.
    • Visual determination of closing volume from SB N2 tracings can be subject to interobserver and intraobserver variability, impacting test reliability.

    Purpose of the Study:

    • To develop and validate a computer program for analyzing the single-breath nitrogen curve.
    • To determine the accuracy and reliability of computer-assisted closing volume calculation compared to traditional visual methods.

    Main Methods:

    • A computer program was developed to analyze the single-breath nitrogen curve by solving regression equations for phases III and IV.
    • Thirty volunteers underwent three consecutive SB N2 tests.
    • Tracings were analyzed both visually by experienced observers and by the computer program.

    Related Experiment Videos

    Main Results:

    • The computer program demonstrated excellent correlation (r = 0.84) with visual determination of closing volume.
    • The computer method showed comparable accuracy to the current visual determination method.

    Conclusions:

    • The developed computer program provides an accurate and reliable method for closing volume analysis.
    • Widespread adoption of this program could save time and enhance the consistency of SB N2 test results by minimizing observer variation.