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The Proteasome02:18

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Eukaryotic cells can degrade proteins through several pathways. One of the most important amongst these is the ubiquitin-proteasome pathway. It helps the cell eliminate the misfolded, damaged, or unwarranted cytoplasmic proteins in a highly specific manner.
In this pathway, the target proteins are first tagged with small proteins called ubiquitin. A series of enzymes carry out the ubiquitination of the target proteins - E1 (ubiquitin-activating enzyme), E2 (ubiquitin-conjugating enzyme), and E3...
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Pathologists Will Prevail

Timothy Craig Allen1

  • 1From the Department of Pathology, The University of Mississippi Medical School, The University of Mississippi Medical Center, Jackson.

Archives of Pathology & Laboratory Medicine
|January 24, 2020
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No abstract available in PubMed .

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