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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Related Experiment Video

Updated: Dec 30, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

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Psoriasis and Co-morbidity.

Mina Amin1, Erica B Lee, Tsen-Fang Tsai

  • 1Department of Dermatology, Kaiser Permanente Los Angeles Medical Center, Los Angeles, USA.

Acta Dermato-Venereologica
|January 24, 2020
PubMed
Summary

Psoriasis patients frequently have other serious health issues, including cardiovascular disease, psoriatic arthritis, and mental health conditions. Early identification and treatment of these comorbidities are crucial for improving patient quality of life.

Keywords:
cardiovascular diseasedepressionimmune-mediated diseasemental health conditionspsoriasispsoriatic arthritis

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Area of Science:

  • Dermatology
  • Rheumatology
  • Cardiology
  • Psychiatry

Background:

  • Psoriasis is a chronic inflammatory condition.
  • Psoriasis is linked to various systemic comorbidities.
  • Understanding these associations is vital for comprehensive patient care.

Purpose of the Study:

  • To evaluate the relationships between psoriasis and cardiovascular disease.
  • To examine the links between psoriasis and psoriatic arthritis.
  • To assess associations with mental health conditions and immune-mediated diseases.

Main Methods:

  • A comprehensive literature search was conducted.
  • The search covered the period from January 1, 2015, to December 18, 2018.
  • Twenty-eight selected studies were included in this review.

Main Results:

  • Psoriasis is associated with cardiovascular disease.
  • Psoriatic arthritis is a common comorbidity.
  • Links to mental health and immune-mediated diseases were also identified.

Conclusions:

  • The relationships between psoriasis and its comorbidities are significant.
  • These associations necessitate consideration in treatment planning.
  • Early recognition and management of comorbidities improve patient outcomes and quality of life.