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Related Experiment Video

Updated: Dec 30, 2025

Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer

Design of an Open-Source, Low-Cost Bioink and Food Melt Extrusion 3D Printer

Published on: March 2, 2020

Assessment methodologies for extrusion-based bioink printability.

Gregory Gillispie^1,2, Peter Prim¹, Joshua Copus^1,2

¹Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, United States of America.

|January 24, 2020

Summary

This summary is machine-generated.

Developing better bioinks for extrusion-based bioprinting requires standardized printability assessments. This review examines current methods to improve bioink development for tissue engineering and regenerative medicine.

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Area of Science:

Bioprinting and Regenerative Medicine
Materials Science

Background:

Extrusion-based bioprinting is crucial for tissue engineering but is limited by the availability of suitable bioinks.
The 'printability' of bioinks, a measure of their suitability for bioprinting, lacks standardized evaluation methodologies, hindering progress.

Purpose of the Study:

To review and analyze existing measures for assessing the printability of extrusion-based bioinks.
To identify gaps and propose future directions for standardizing bioink printability assessments.

Main Methods:

Literature review of quantitative and qualitative methods used to evaluate bioink printability.
Categorization of printability aspects including extrudability, shape fidelity, and printing accuracy.

Main Results:

A wide variety of printability assessment methods exist, with varying degrees of quantitative rigor.
Many researchers do not evaluate bioink printability, or do so only qualitatively.
Existing quantitative measures focus on specific aspects like extrudability and shape fidelity, but a comprehensive approach is lacking.

Conclusions:

Standardization of bioink printability assessment methodologies is essential for advancing bioink development.
Improved and standardized assessment techniques will lead to a better understanding of bioink properties and facilitate more reliable comparisons.
This will ultimately enhance the development of novel bioinks for tissue engineering and regenerative medicine applications.