Related Experiment Video
Updated: Dec 30, 2025

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
Published on: August 9, 2024
Computational time series analysis of patient referrals to a primary percutaneous coronary intervention service
Aleeha Iftikhar, Raymond R Bond, Victoria McGilligan1
1Ulster University, UK.
Insights
This study analyzed percutaneous coronary intervention referrals, finding most were male and occurred
Area of Science:
- Cardiology
- Health Services Research
Background:
- Percutaneous coronary intervention (PCI) is a critical cardiac procedure.
- Understanding referral patterns is key to optimizing cardiac care access.
Purpose of the Study:
- To analyze trends and characteristics of PCI referrals.
- To investigate factors influencing referral acceptance and rejection.
- To assess the impact of referral timing on patient outcomes.
Main Methods:
- Retrospective analysis of a PCI dataset (2015-2018).
- Time series analysis of referral rates (yearly, monthly, daily, hourly).
- Statistical analysis of patient demographics, referral timing, and outcomes.
Main Results:
- 70% of referrals were male; 65% were 'out of hours'.
- Referral numbers did not correlate with turndown rates.
- Female patients were more likely to be referred 'out of hours'.
- Higher 30-day mortality was observed in the turndown group.
- The average age of patients in the turndown group was higher.
Conclusions:
- Referral patterns exhibit significant temporal variation.
- Out-of-hours referrals, particularly for females, are prevalent.
- A 24/7 cardiac catheterization laboratory service is essential for timely PCI.
- Referral volume does not influence clinical decision-making regarding PCI acceptance.
Abstract:
This article retrospectively analyses a primary percutaneous coronary intervention dataset comprising patient referrals that were accepted for percutaneous coronary intervention and those who were turned down between January 2015 and December 2018 at Altnagelvin Hospital (United Kingdom). Time series analysis of these referrals was undertaken for analysing the referral rates per year, month, day and per hour. The overall referrals have 70 per cent (n = 1466, p < 0.001) males. Of total referrals, 65 per cent (p < 0.001) of referrals were 'out of hours'. Seasonality decomposition shows a peak in referrals on average every 3 months (standard deviation = 0.83). No significant correlation (R = 0.03, p = 0.86; R = -0.11, p = 0.62) was found between the referral numbers and turndown rate. Being female increased the probability of being out of hour in all the groups. The 30-day mortality was higher in the turndown group. The time series of all the referrals depict variation over the months or days which is not the same each year. The average age of the patients in the turndown group is higher. The number of referrals does not impact on the turndown rate and clinical decision making. Most patients are being referred out of hours, especially females. This analysis leads to the emphasis on the importance of working 24/7 CathLab service.
More Related Videos
05:41Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
Published on: December 16, 2022
18:11A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
Published on: December 28, 2012
Related Concept Videos
Coronary Artery Disease V: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Acute Coronary Syndrome III: Diagnostic Studies
Introduction To Survival Analysis
The primary goal of survival analysis is to estimate survival time—the time...