Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ribozymes02:47

Ribozymes

13.2K
The term ribozyme is used for RNA that can act as an enzyme. Ribozymes are mainly found in selected viruses, bacteria, plant organelles, and lower eukaryotes. Ribozymes were first discovered in 1982 when Tom Cech’s laboratory observed Group I introns acting as enzymes. This was shortly followed by the discovery of another ribozyme, Ribonulcease P, by Sid Altman’s laboratory. Both Cech and Altman received the Nobel Prize in chemistry in 1989 for their work on ribozymes.
Ribozymes can...
13.2K
Synthetic Biology02:55

Synthetic Biology

5.4K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.4K
Enzymes02:34

Enzymes

92.6K
Inside living organisms, enzymes act as catalysts for many biochemical reactions involved in cellular metabolism. The role of enzymes is to reduce the activation energies of biochemical reactions by forming complexes with its substrates. The lowering of activation energies favor an increase in the rates of biochemical reactions.
Enzyme deficiencies can often translate into life-threatening diseases. For example, a genetic abnormality resulting in the deficiency of the enzyme G6PD...
92.6K
Introduction to Enzymes01:22

Introduction to Enzymes

30.7K
The use of enzymes by humans dates to 7000 BCE. Humans first used enzymes to ferment sugars and produce alcohol without knowing that this was an enzyme-catalyzed reaction. Wilhelm Kuhne coined the term 'enzyme' in 1877 from the Greek words ‘en’ meaning ‘in’ or ‘within’ and ‘zyme’ meaning ‘yeast.’
Most enzymes are proteins that speed up biochemical reactions without being consumed. Enzymes contain one or more active sites that...
30.7K
Biosynthesis in Bacteria01:24

Biosynthesis in Bacteria

485
Biosynthesis in bacteria is a fundamental anabolic process that generates essential macromolecules, including proteins, nucleic acids, lipids, and polysaccharides. These macromolecules are critical for cellular growth, replication, and function. The process is tightly regulated and energetically linked to catabolic pathways to ensure optimal resource utilization.Biosynthetic pathways begin with precursor metabolites such as pyruvate, acetyl-CoA, and glucose-6-phosphate derived from glycolysis,...
485

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical outcomes of immune checkpoint inhibitor based therapy in NRG1 fusion positive non small cell lung cancer a retrospective study.

Discover oncology·2026
Same author

An injectable Ce-MnCo LDH nanozyme gel with cascade catalytic activity for acute radiation proctitis in rats.

Biomaterials·2026
Same author

Antioxidant Nanozymes: From Rational Design to Biomedical Applications.

Research (Washington, D.C.)·2026
Same author

Atomic-Scale Full-Size Engineering of Platinum Nanozymes Enables High-Efficiency Catalytic Therapy.

ACS nano·2026
Same author

An inhalable nanozyme for STING blockade to treat radiation-induced lung injury.

Journal of nanobiotechnology·2026
Same author

Piezocatalytic nanotransducers rewire tumor immunometabolism via in situ peroxynitrite generation.

Biomaterials·2026

Related Experiment Video

Updated: Dec 30, 2025

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

1.4K

Nanozymes: created by learning from nature.

Ruofei Zhang1, Kelong Fan2,3, Xiyun Yan4,5

  • 1CAS Engineering Laboratory for Nanozyme, Key Laboratory of Protein and Peptide Pharmaceutical, Institute of Biophysics, Chinese Academy of Sciences, Beijing, 100101, China.

Science China. Life Sciences
|January 25, 2020
PubMed
Summary
This summary is machine-generated.

Bio-inspired nanozymes leverage natural enzyme structures to enhance catalytic efficiency and substrate specificity. This review explores strategies, progress, and challenges in developing these advanced nanomaterials for broader applications.

Keywords:
bio-inspiredbio-mimic active centercofactorsenzyme-like activitynanozymesingle-atom catalysis

More Related Videos

Detection of Bacteria Using Fluorogenic DNAzymes
13:20

Detection of Bacteria Using Fluorogenic DNAzymes

Published on: May 28, 2012

19.6K
Designing a Bio-responsive Robot from DNA Origami
13:32

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

22.7K

Related Experiment Videos

Last Updated: Dec 30, 2025

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection
07:16

Author Spotlight: Advancements in DNA Nanosensors – Addressing Sensitivity and Selectivity Challenges in Molecular Detection

Published on: February 9, 2024

1.4K
Detection of Bacteria Using Fluorogenic DNAzymes
13:20

Detection of Bacteria Using Fluorogenic DNAzymes

Published on: May 28, 2012

19.6K
Designing a Bio-responsive Robot from DNA Origami
13:32

Designing a Bio-responsive Robot from DNA Origami

Published on: July 8, 2013

22.7K

Area of Science:

  • Nanomaterials Science
  • Biochemistry
  • Catalysis

Background:

  • Nanozymes, nanomaterials with enzyme-like activity, offer potential replacements for natural enzymes in diverse applications.
  • Current nanozymes require improved catalytic efficiency and substrate specificity for wider adoption.
  • Bio-inspired design strategies are emerging to address these limitations.

Purpose of the Study:

  • To review bio-inspired strategies for creating nanozymes.
  • To clarify the current progress and identify bottlenecks in nanozyme development.
  • To provide insights for the rational design of advanced nanozymes.

Main Methods:

  • Literature review of bio-inspired strategies for nanozyme design.
  • Analysis of methods mimicking natural enzyme cofactors and active centers.
  • Synthesis and characterization of bio-inspired nanozymes.

Main Results:

  • Bio-inspired strategies, including cofactor mimicry and active site simulation, enhance nanozyme performance.
  • These approaches improve catalytic efficiency and substrate specificity compared to conventional nanozymes.
  • The review outlines key advances and remaining challenges in the field.

Conclusions:

  • Bio-inspired design is a promising avenue for developing high-performance nanozymes.
  • Further research is needed to overcome current limitations and achieve ideal nanozyme characteristics.
  • These advancements pave the way for novel applications in diagnostics, therapeutics, and environmental remediation.