Related Experiment Video
Updated: Dec 30, 2025
Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
Published on: September 9, 2022
Autoimmune Encephalitis
1Dr. Zandi is with the Institute of Neurology, University College London, London, United Kingdom, and with the National Institute for Health Research, University College London Hospitals Biomedical Research Centre. Address correspondence to Dr. Zandi at the UCL Institute of Neurology, Queen Square House, Queen Square, London, United Kingdom.
Abstract:
Antibodies to brain cell-surface proteins have recently been identified in patients whose symptoms cross the boundary between neurology and psychiatry and are associated with syndromes that are responsive to treatment with immunosuppression-based treatments. This has led to an expansion in the field of autoimmune encephalitis. The common syndromes, with particular relevance to psychiatry, are discussed, in particular the N-methyl-d-aspartate receptor antibody encephalitis syndrome, which is most often associated with a psychosis and cognitive prodrome resembling acute or first-episode psychosis. The recognition, clinical diagnosis and associations, and evidence for disease mechanisms are discussed in this brief review.
