Related Experiment Video
Updated: Dec 30, 2025

Social Isolation Model: A Noninvasive Rodent Model of Stress and Anxiety
Published on: November 11, 2022
Anxiety Disorders and General Medical Conditions: Current Research and Future Directions
Joshua P Aquin1, Renée El-Gabalawy1, Tanya Sala1
1Mr. Aquin is a medical student at the Max Rady College of Medicine; Dr. El-Gabalawy is an assistant professor, Department of Anesthesia, Perioperative Medicine, Clinical Health Psychology, Psychiatry and Psychology; Dr. Sala is the medical program director, Mood and Anxiety Disorders Program of the Health Sciences Centre, and assistant professor, Department of Psychiatry; and Dr. Sareen is a professor of Psychiatry in the Departments of Psychiatry, Psychology, and Community Health Sciences, all at the University of Manitoba, Winnipeg, Manitoba, Canada.
Abstract:
Evidence that anxiety disorders are associated with general medical conditions is growing. While it is known that medical and mental conditions are often comorbid, research demonstrates that there may be underlying causal mechanisms. Furthermore, comorbid anxiety and general medical conditions are associated with poorer patient outcomes than either condition alone. Comorbid general medical and mental disorders not only affect individual patient health but also strain existing medical systems. Growing health care expenditures and increasing time pressures on clinicians create a challenging environment for intensive therapy in traditional settings. Effective screening, diagnosis, and treatment of individuals with comorbid conditions require health systems that are based on interprofessional collaboration, including integrative and collaborative care services. These models encourage the provision of patient care within a network of health care professionals, working together and sharing expertise for more efficient and holistic care. Research on the design and implementation of these systems within the context of anxiety disorders and comorbid general medical conditions is in its infancy. Given the staggeringly high rates of anxiety disorders within the general population and the continued rise of many chronic medical conditions coinciding with the increasing lifespan, mental health and primary care providers should consider how they might implement integrative care methods within their own practice.
Related Concept Videos
Anxiety: Overview
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
Generalized Anxiety Disorder
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Panic Disorder
Social Anxiety Disorder
Anxiolytic Drugs: Overview
Primary Types of Anxiolytic Drugs
1. Benzodiazepines:
Benzodiazepines bind to the GABA-A receptor in the brain, enhancing GABA's interaction. This action reduces neurotransmission, effectively blocking anxiety-associated limbic...

