Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

479
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
479
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

715
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
715
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

347
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
347
Therapeutic Drug Monitoring: Affecting Factors01:29

Therapeutic Drug Monitoring: Affecting Factors

142
Therapeutic Drug Monitoring (TDM) is the clinical practice of measuring specific drug levels in a patient's blood or body tissues to manage and optimize therapy. TDM is crucial for drugs with narrow therapeutic windows, like warfarin and phenytoin, where incorrect doses can lead to treatment failure or severe side effects. This monitoring ensures the dosage administered is within a safe and effective range. The factors affecting therapeutic drug monitoring include:Patient-Specific Factors:a.
142

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Use of Vagus Nerve Stimulation (VNS) in the Management of Patients with Difficult-to-Treat Major Depressive Disorder (MDD): An Expert Consensus Statement.

Neuropsychiatric disease and treatment·2026
Same author

Is It Time for a Universal Outcome Measure to Deliver on the Promises of Interventional Psychiatry?

The American journal of psychiatry·2026
Same author

Derivation of an updated brief multivariable prediction model to detect panic-related anxiety in emergency department patients with cardiopulmonary complaints.

Frontiers in psychiatry·2026
Same author

Assessing symptom severity in patients with markedly treatment-resistant depression: Insights from the RECOVER trial.

Journal of affective disorders·2026
Same author

Factors associated with interpersonal retraumatization in children and adolescents: A prospective study.

Psychiatry research·2025
Same author

The trajectory of symptom change over the course of transcranial magnetic stimulation for major depressive disorder.

Brain stimulation·2025

Related Experiment Video

Updated: Dec 30, 2025

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K

A Clinician's Perspective on Biomarkers.

A John Rush1, Hicham M Ibrahim1

  • 1Dr. Rush is professor emeritus, Duke-National University of Singapore, Singapore; adjunct professor at the Department of Psychiatry, Duke University Medical School, Durham, North Carolina, and at the Department of Psychiatry, Texas Tech University Health Sciences Center, Permina Basin. Dr. Ibrahim is with the Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas.

Focus (American Psychiatric Publishing)
|January 25, 2020
PubMed
Summary

Biomarkers, including genetic and physiological measures, promise greater precision in mental health care. These biological markers aid in diagnosis, prognosis, and treatment selection, improving patient outcomes.

Keywords:
bio-measuresbiomarkerprognostication. diagnosispsychiatrytreatment selection

More Related Videos

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

16.1K
Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
05:19

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment

Published on: July 7, 2023

3.1K

Related Experiment Videos

Last Updated: Dec 30, 2025

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

37.1K
Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data
14:27

Identification of Disease-related Spatial Covariance Patterns using Neuroimaging Data

Published on: June 26, 2013

16.1K
Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment
05:19

Author Spotlight: Therapeutic Benefit of Closed-Loop Deep Brain Stimulation in Depression Treatment

Published on: July 7, 2023

3.1K

Area of Science:

  • Neuroscience
  • Psychiatry
  • Biomarker Research

Background:

  • Mental health professionals perform critical clinical tasks impacting patient outcomes.
  • Measurement-based care has enhanced precision and improved outcomes in psychiatric practice.
  • Biomarkers are emerging tools with the potential to revolutionize mental health diagnostics and treatment.

Purpose of the Study:

  • To provide an overview of biomeasures and biomarkers in mental health.
  • To discuss the clinical applications of biomarkers.
  • To highlight challenges in biomarker development and implementation.

Main Methods:

  • Review of current literature on biomeasures and biomarkers in psychiatry.
  • Categorization of potential biomarkers (genetic, proteomic, physiological, etc.).
  • Analysis of biomarker functions: diagnostic, prognostic, and theranostic.

Main Results:

  • Biomeasures encompass genetic, proteomic, metabolomic, immunologic, physiological, functional, and brain structural data.
  • Biomarkers can be mechanistic, diagnostic, prognostic, or theranostic.
  • Applications include risk assessment, diagnosis, treatment selection, and monitoring treatment effects.

Conclusions:

  • Biomarkers hold significant promise for advancing precision in mental health care.
  • Further development and clinical integration of biomarkers are crucial for improved patient outcomes.
  • Biomarkers are expected to enhance diagnostic accuracy, treatment efficacy, and patient management in psychiatry.