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Related Concept Videos

Breathing01:05

Breathing

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The process of breathing, inhaling and exhaling, involves the coordinated movement of the chest wall, the lungs, and the muscles that move them. Two muscle groups with important roles in breathing are the diaphragm, located directly below the lungs, and the intercostal muscles, which lie between the ribs. When the diaphragm contracts, it moves downward, increasing the volume of the thoracic cavity and creating more room for the lungs to expand. When the intercostal muscles contract, the ribs...
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Overview of Respiratory System01:23

Overview of Respiratory System

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The respiratory system is a complex biological apparatus that facilitates the exchange of gases, specifically oxygen and carbon dioxide, between our bodies and the environment. This system plays a vital role in the physiological process of respiration, an essential function for sustaining life.
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The Respiratory System01:16

The Respiratory System

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The respiratory system is comprised of the organs that enable breathing. Air enters the nostrils and mouth, followed by the pharynx (throat) and larynx (voice box), which lead to the trachea (windpipe). In the thoracic cavity, the trachea splits into two bronchi that allow air to enter the lungs. The bronchi split into progressively smaller bronchioles and terminate in small groups of tiny sacs in the lungs called alveoli, where gas exchange occurs.
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Assessment of Diffusion and Perfusion01:17

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Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
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Assessment of Respiration01:23

Assessment of Respiration

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The respiratory system's basic structures and primary functions lay the foundation for nurses' comprehensive respiratory assessments. This assessment includes subjective and objective data to gauge the patient's respiratory health.
Subjective Assessment: Nurses interview the patient to gather information directly during the subjective assessment. It includes questions about the individual's medical history, medications, and symptoms, focusing on past respiratory conditions like...
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Respiration and Gaseous Exchange01:20

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The intricate interplay between the cardiovascular and respiratory systems is crucial for efficiently transporting respiratory gases throughout the body. Let us explore the cardiovascular system's multifaceted functions, emphasizing its pivotal role in gas exchange.
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Related Experiment Video

Updated: Dec 30, 2025

Breath Collection from Children for Disease Biomarker Discovery
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Breath Collection from Children for Disease Biomarker Discovery

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Human Breathomics Database.

Tien-Chueh Kuo1,2,3, Cheng-En Tan2,3,4, San-Yuan Wang2,4,5

  • 1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 10617, Taiwan.

Database : the Journal of Biological Databases and Curation
|January 25, 2020
PubMed
Summary
This summary is machine-generated.

Researchers developed the Human Breathomics Database (HBDB), a comprehensive resource linking volatile organic compounds (VOCs) in exhaled breath to diseases. This database aids in identifying potential breath biomarkers for clinical use.

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Area of Science:

  • Breathomics
  • Metabolomics
  • Biomarker Discovery

Background:

  • Breathomics analyzes volatile organic compounds (VOCs) in exhaled breath.
  • Linking VOCs to diseases is challenging due to fragmented literature.
  • An organized resource is needed for breath molecule research.

Purpose of the Study:

  • To create a comprehensive database of breath VOCs, their associated diseases, and references.
  • To integrate manually curated and automatically extracted biomedical information.
  • To establish the Human Breathomics Database (HBDB).

Main Methods:

  • Manual curation of VOC-disease information from 207 publications (99 VOCs).
  • Automated text mining to extract biomedical information from 2766 publications.
  • Combined curated and extracted data to build the HBDB.

Main Results:

  • The HBDB contains 913 VOCs linked to human breath research.
  • Information includes references, VOCs, and associated diseases.
  • The database integrates data from 2766 publications.

Conclusions:

  • The HBDB is the most comprehensive resource for VOCs in human exhaled breath.
  • It serves as a valuable tool for researchers and clinicians.
  • Facilitates identification and investigation of potential breath biomarkers.