Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

4.7K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
4.7K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

3.0K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
3.0K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

1.9K
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
1.9K
Psychoneuroimmunology: Diabetes and Cancer01:19

Psychoneuroimmunology: Diabetes and Cancer

369
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
369
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

4.2K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
4.2K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Explainable AI for Equitable Nurse Scheduling: Pragmatic Pre-Post Implementation Study.

JMIR nursing·2026
Same author

Benefits and harms of copyright restrictions and conditions on burnout and other psychometric assessment scales.

PloS one·2026
Same author

Seasonal variation in climate, air pollution, and the incidence of benign paroxysmal positional vertigo.

Scientific reports·2026
Same author

Increased prevalence of hearing loss and tinnitus in patients with retinal vein occlusion.

Scientific reports·2026
Same author

Association between pre-diagnostic prevalence of 30 common diseases and the subsequent risk of dementia: a population-based retrospective cohort study in Taiwan.

Frontiers in aging neuroscience·2026
Same author

Beneficial bystander-enhanced cryptic splice rescue of cardiac-type Fabry GLA IVS4+919G>A by adenine base editing in patient fibroblasts.

Gene therapy·2026

Related Experiment Video

Updated: Dec 30, 2025

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.4K

Malignant Otitis Externa is Associated with Diabetes: A Population-Based Case-Control Study.

Tzong-Hann Yang1,2,3, Sudha Xirasagar4, Yen-Fu Cheng2,5,6,7

  • 1Department of Otorhinolaryngology, Taipei City Hospital, Taipei.

The Annals of Otology, Rhinology, and Laryngology
|January 25, 2020
PubMed
Summary

Malignant otitis externa (MOE) is strongly linked to diabetes. This study found patients with diabetes are 10 times more likely to develop MOE, highlighting the need for clinical awareness.

Keywords:
diabetesepidemiologymalignant otitis externa

More Related Videos

Whole-mount Confocal Microscopy for Adult Ear Skin: A Model System to Study Neuro-vascular Branching Morphogenesis and Immune Cell Distribution
08:42

Whole-mount Confocal Microscopy for Adult Ear Skin: A Model System to Study Neuro-vascular Branching Morphogenesis and Immune Cell Distribution

Published on: March 29, 2018

13.9K
Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
08:02

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

10.3K

Related Experiment Videos

Last Updated: Dec 30, 2025

Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.4K
Whole-mount Confocal Microscopy for Adult Ear Skin: A Model System to Study Neuro-vascular Branching Morphogenesis and Immune Cell Distribution
08:42

Whole-mount Confocal Microscopy for Adult Ear Skin: A Model System to Study Neuro-vascular Branching Morphogenesis and Immune Cell Distribution

Published on: March 29, 2018

13.9K
Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice
08:02

Th17 Inflammation Model of Oropharyngeal Candidiasis in Immunodeficient Mice

Published on: February 18, 2015

10.3K

Area of Science:

  • Otolaryngology
  • Endocrinology
  • Epidemiology

Background:

  • Malignant otitis externa (MOE) is a severe external ear infection.
  • Previous studies suggest a link between MOE and diabetes, but large-scale evidence is lacking.

Purpose of the Study:

  • To investigate the association between previously diagnosed diabetes and the occurrence of MOE using a nationwide population-based study.

Main Methods:

  • A population-based case-control study utilizing Taiwan's National Health Insurance Research Database.
  • Included 753 MOE cases and 2,259 propensity score-matched controls.
  • Analyzed data using multiple logistic regressions to assess the association.

Main Results:

  • Diabetes was diagnosed in 54.8% of MOE cases versus 13.9% of controls (p < 0.001).
  • The adjusted odds ratio for prior diabetes in MOE cases was 10.07 (95% CI, 8.15–12.44).
  • A significant association between MOE and pre-existing diabetes was confirmed.

Conclusions:

  • This study confirms a significant association between malignant otitis externa and diabetes.
  • Physicians should consider MOE in diabetic patients presenting with ear canal swelling or granulation, especially with otalgia or otorrhea.