Longitudinal cohort study reveals different patterns of stress in parents of preterm infants during the first year after birth
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Updated: Dec 30, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Annika Schmöker1,2, Renée Flacking2, Camilla Udo2,3,4
1Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Insights
Parental stress in the first year after preterm birth differs between mothers and fathers. Mothers experienced decreasing stress, while fathers
Area of Science:
- Neonatal care
- Parental mental health
- Psychosocial outcomes
Background:
- Parental stress is a significant concern for families with preterm infants.
- Understanding gender-specific stress trajectories is crucial for effective support.
- The transition to parenthood with a preterm infant presents unique challenges.
Purpose of the Study:
- To compare maternal and paternal stress experiences during the first year of life for preterm infants.
- To assess changes in parental stress over time.
- To identify predictors of parental stress in this population.
Main Methods:
- Longitudinal study collecting parental stress data at 8 weeks, 6 months, and 12 months postpartum.
- Inclusion of 493 mothers and 329 fathers of 547 preterm infants in Sweden.
- Utilized the Swedish Parenting Stress Questionnaire as a secondary outcome in a randomized clinical trial.
Main Results:
- Mothers reported higher role restriction, fathers higher social isolation.
- Maternal stress decreased over the first year; paternal stress increased between 6 and 12 months.
- Higher stress levels were associated with very preterm infants, twins, and lower parental general health.
Conclusions:
- Mothers and fathers exhibit distinct patterns of stress development post-preterm birth.
- These differing stress trajectories suggest tailored support strategies are needed.
- Timing of postnatal support may need to be individualized based on parental gender and specific infant characteristics.
Aim:
To compare experiences of stress in mothers and fathers of preterm infants during the first year of life, assess changes in parental stress and explore potential predictors of parental stress.
Methods:
Between 2013 and 2015, data on parental stress were collected at 8 weeks after discharge and at 6 and 12 months postpartum from 493 mothers and 329 fathers of 547 preterm infants in Sweden. The Swedish Parenting Stress Questionnaire was used as a secondary outcome in a randomised clinical trial of breastfeeding support.
Results:
At the three time points, mothers perceived more role restriction and fathers more social isolation (P < .001). Stress decreased in mothers during the first year (P = .018), whereas stress increased in fathers between 6 and 12 months (P = .048). Mothers of very preterm infants (P = .024), parents of twins (P = .038) and parents with lower perceived general health (P = .003) reported higher levels of stress during the first year after birth.
Conclusion:
This study identified several factors that influenced parental stress. Mothers and fathers showed different patterns of stress levels during the first year after birth. This finding indicates different needs for mothers and fathers regarding the time at which parental support after discharge might be most beneficial.
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