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Updated: Dec 30, 2025

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
Synthesis of Stereodefined Trisubstituted Alkenyl Silanes Enabled by Borane Catalysis and Nickel Catalysis
Yunxiao Zhang1, Yanran Chen1, Zeguo Zhang1
1Institute for Advanced Studies, Engineering Research Center of Organosilicon Compounds & Materials, Ministry of Education , Wuhan University , 299 Bayi Road , Wuhan , Hubei 430072 , China.
Abstract:
Regioselective and stereoselective synthesis of trisubstituted alkenyl silanes via hydrosilylation is challenging. Herein, we report the first β-anti-selective addition of silanes to thioalkynes with B(C6F5)3 as the catalyst. The reaction shows broad substrate scope. The products were proven to be useful intermediates to other trisubstituted alkenyl silanes by Ni-catalyzed stereoretentive cross-coupling reactions of the C-S bond. A mechanism study suggests that nucleophilic attack of thioalkyne to an activated silylium intermediate might be the rate-determining step.
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