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Oral mite anaphylaxis: who, when, and how?
Mario Sánchez-Borges1,2, Arnaldo Capriles-Hulett1, Enrique Fernandez-Caldas3,4
1Allergy and Clinical Immunology Department, Centro Médico Docente La Trinidad.
Current Opinion in Allergy and Clinical Immunology
|January 25, 2020
Summary
Oral mite anaphylaxis (OMA), or pancake syndrome, is a severe allergic reaction. Recent findings show increased prevalence in children, association with exercise-induced anaphylaxis, and potential for severe outcomes.
Area of Science:
- Allergy and Immunology
- Food Allergy Research
- Clinical Medicine
Background:
- Oral mite anaphylaxis (OMA), also known as pancake syndrome, is a severe allergic reaction.
- It is triggered by the ingestion of foods contaminated with mites.
Purpose of the Study:
- To provide an updated review of the latest advancements in understanding the mechanisms of OMA.
- To discuss the practical management strategies for oral mite anaphylaxis.
- To highlight recent findings and their clinical implications.
Main Methods:
- Literature review of recent studies on oral mite anaphylaxis.
- Synthesis of novel observations and clinical data.
- Analysis of diagnostic and management approaches.
Main Results:
- Increased prevalence of aspirin/NSAID hypersensitivity in OMA patients.
- Association between OMA and exercise-induced anaphylaxis.
- OMA can mimic acute asthma and occurs in childhood.
- High severity and lethal potential of OMA are noted.
- Mite contamination extends to oat and corn flour.
- Simultaneous OMA induction in multiple individuals exposed to the same food.
Conclusions:
- OMA is a severe, potentially lethal allergic condition.
- Suspicion should arise with symptoms following mite-contaminated food intake.
- Physician awareness is crucial for diagnosis and prevention.
- Adequate preventive measures are essential for at-risk patients.
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