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Updated: Dec 30, 2025

Non-Invasive PET/MR Imaging in an Orthotopic Mouse Model of Hepatocellular Carcinoma
Published on: August 31, 2022
Primary Hepatocellular Carcinoma With Intense 68Ga-PSMA Uptake But Slight 18F-FDG Uptake on PET/CT Imaging
Seval Erhamamci1, Nesrin Aslan2
1From the Department of Nuclear Medicine, Baskent University Faculty of Medicine.
Abstract:
Ga-PSMA PET/CT imaging is an emerging imaging modality in prostate cancer. PSMA expression is also reported for nonprostate malignancies, including primary hepatocellular carcinoma. Herein, we present a case of a 74-year-ald man with recently diagnosed hepatocellular carcinoma who was referred for F-FDG PET/CT imaging for initial staging. The patient underwent F-FDG PET/CT as part of staging procedure; he also underwent Ga-PSMA PET/CT. PET/CT images revealed only slight F-FDG uptake in the liver lesion, but intense Ga-PSMA uptake, without any metastatic lesion seen elsewhere in the body.
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