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Acquired segmental sigmoid hypoganglionosis: A case report.
Zhi-Ping Pan1, Lu-Qiao Huang2, Jun-Hui Cui2
1The Second Clinical Medical College, Zhejiang Chinese Medical University.
Medicine
|January 25, 2020
Summary
Acquired segmental hypoganglionosis is rare in adults. Surgical resection and colostomy effectively treated a 48-year-old woman with this condition, improving colorectal dilatation.
Area of Science:
- Gastroenterology
- Colorectal Surgery
- Pediatric Surgery
Background:
- Intestinal hypoganglionosis typically affects infants and children, with adult diagnoses being infrequent.
- Adult cases are often identified post-operatively for chronic constipation and megacolon.
Observation:
- A 48-year-old female presented with a two-month history of bowel movement cessation and an abdominal mass.
- Diagnostic imaging revealed colonic dilatation and sigmoid wall thickening; anorectal manometry showed anal sphincter relaxation.
Findings:
- Histological examination confirmed acquired segmental sigmoid hypoganglionosis, noting reduced ganglion cells.
- The patient underwent sigmoidectomy and transverse colostomy, with a successful recovery.
Implications:
- This case highlights acquired segmental hypoganglionosis in adults, emphasizing the need for clinical awareness.
- Surgical intervention, including resection and enterostomy, offers an effective treatment strategy for managing this condition and preventing complications.
