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Parent IMPACT-III: Development and Validation of an Inflammatory Bowel Disease-specific Health-related
Grace K Cushman1, Mary Gray Stolz1, Sharon Shih2
1University of Georgia.
Insights
The parent-proxy IMPACT-III (IMPACT-III-P) is a valid and reliable tool for assessing health-related quality of life (HRQOL) in pediatric inflammatory bowel disease (IBD) patients. This measure offers valuable insights for understanding HRQOL in youth with IBD.
Area of Science:
- Pediatric Gastroenterology
- Health Outcomes Research
- Psychosocial Assessment
Background:
- Parent-proxy report measures are crucial for pediatric psychosocial assessments.
- The IMPACT-III-P aims to provide a comprehensive representation of health-related quality of life (HRQOL) in youth with inflammatory bowel disease (IBD).
Purpose of the Study:
- To validate the parent-proxy version of the IMPACT-III (IMPACT-III-P) in a sample of youth diagnosed with IBD.
- To assess the reliability and validity of the IMPACT-III-P for measuring HRQOL in pediatric IBD patients.
Main Methods:
- Parents (N=50) of youth aged 8-17 with IBD completed the IMPACT-III-P, PedsQL-4.0, and BASC-2.
- Youth reported on their HRQOL (child IMPACT-III), pain interference, and disease symptoms.
- Physicians assessed disease activity.
Main Results:
- The IMPACT-III-P demonstrated strong criterion validity, correlating positively with the PedsQL (r=0.59).
- Convergent validity was supported by associations with less pain interference and lower depression scores (r=-0.41 for both).
- Reliability analyses, including internal consistency and parent-child agreement, revealed strong results.
Conclusions:
- The IMPACT-III-P is a valid and reliable measure for assessing HRQOL in youth aged 8-17 with IBD.
- Findings support the use of IMPACT-III-P alongside the child IMPACT-III for comprehensive HRQOL evaluation in pediatric IBD.
- Parents and children reported similar HRQOL, with parents rating it slightly lower.
Objectives:
The present study aimed to validate the parent-proxy IMPACT-III (IMPACT-III-P) in a sample of youth diagnosed with inflammatory bowel disease (IBD). Parent-proxy report measures are standard for pediatric psychosocial assessment, and the IMPACT-III-P will provide a more comprehensive representation of HRQOL. Reliability and validity analyses were conducted.
Methods:
Parents (N = 50) of youth 8 to 17 years with IBD reported on their child's HRQOL (IMPACT-III-P and PedsQL-4.0) and depression (BASC-2); youth reported on their HRQOL (child IMPACT-III), pain interference (PROMIS Pain Interference), and disease symptoms; and physicians completed measures of disease activity.
Results:
Criterion validity was established as the IMPACT-III-P was strongly, positively associated with the PedsQL (r = 0.59, P < 0.001). Convergent validity was supported as higher IMPACT-III-P scores were associated with less pain interference (r = -0.41, P < 0.01) and lower depression (r = -0.41, P < 0.01). Discriminant validity was partially supported, as higher IMPACT-III-P scores were associated with lower child-reported symptoms (r = -0.41, P < 0.01), but scores did not differ based on inactive, mild, or moderate/severe disease activity groups as rated by physicians. Internal consistency, parent-child agreement, and item-level analyses revealed strong reliability.
Conclusions:
The IMPACT-III-P demonstrated strong validity and reliability. Parents and children had similar reports of HRQOL, with parents rating child HRQOL slightly lower. Findings support the use of the IMPACT-III-P for youth 8 to 17 years old to use in accordance with the child IMPACT-III to provide valuable information regarding HRQOL in youth with IBD.
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