Related Experiment Video

Updated: Dec 30, 2025

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children
10:57

Determining Soil-transmitted Helminth Infection Status and Physical Fitness of School-aged Children

Published on: August 22, 2012

24.2K

Persistent Soiling Affects Quality of Life in Children With Hirschsprung's Disease

Lucile Espeso1, Audrey Coutable2, Valérie Flaum3

  • 1Department of Pediatric Gastro-enterology, University Hospital, Bordeaux.

Journal of Pediatric Gastroenterology and Nutrition
|January 25, 2020
PubMed

Insights

Soiling issues significantly impact the quality of life (QOL) for children with Hirschsprung

Area of Science:

  • Pediatric Surgery
  • Gastroenterology
  • Quality of Life Research

Background:

  • Hirschsprung's disease (HD) is a congenital condition affecting the large intestine.
  • Long-term outcomes and quality of life (QOL) in pediatric patients with HD require ongoing evaluation.

Purpose of the Study:

  • To assess the quality of life (QOL) in children and adolescents diagnosed with Hirschsprung's disease (HD).
  • To identify factors associated with QOL in HD patients.

Main Methods:

  • A multicentric study included 63 pediatric patients (6-18 years) with HD.
  • Quality of life was measured using the Health Utilities Index (HAQL) questionnaires, completed by patients and parents.
  • Data were correlated with disease characteristics, nutritional status, and functional scores.

Main Results:

  • Only 50-68% of patients achieved satisfactory bowel movements; 55-70% experienced soiling issues.
  • Lower QOL scores were observed in patients with soiling, particularly concerning general well-being and diurnal fecal continence.
  • Multivariate analysis identified soiling as the sole significant factor negatively impacting QOL (P=0.03).

Conclusions:

  • Soiling is a prevalent complication in children treated for HD, substantially diminishing their QOL.
  • Prioritizing the assessment and management of soiling is crucial for improving the long-term QOL of HD patients.
Abstract

More Related Videos

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.505:45

Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5

Published on: April 26, 2019

14.0K
Oral Biofilm Sampling for Microbiome Analysis in Healthy Children10:42

Oral Biofilm Sampling for Microbiome Analysis in Healthy Children

Published on: December 31, 2017

17.7K

Related Concept Videos

Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
700
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
962
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
586
Ostomy Care01:24

Ostomy Care

Introduction
An ostomy is a surgical procedure that creates an artificial opening from the intestines to the outside of the body, allowing for the rerouting of effluent. This opening is known as a stoma. A stoma usually protrudes above the skin surface, appearing pink or red, moist, and round, and it lacks nerve sensations.
There are different types of ostomies, including colostomies, ileostomies, and urostomies:
1.6K
Drugs for Treatment of Constipation-Predominant IBS01:21

Drugs for Treatment of Constipation-Predominant IBS

Pharmacological therapies for IBS-C are designed to alleviate abdominal discomfort and enhance bowel function. In patients with IBS-C, fiber supplements may help soften stools and decrease straining, but may also lead to increased gas production and bloating. Osmotic laxatives like milk of magnesia are frequently used to soften stools and increase stool frequency in IBS-C patients. In addition, two drugs approved for use in severe IBS-C adult cases are linaclotide (Linzess) and lubiprostone...
629
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
384