Related Experiment Videos
Ciprofloxacin in elderly patients with underlying chronic diseases
W Bianchi1, F Maggiolo, H Ohnmeiss
1Medical Department, Bayer Italia SpA, Milan, Italy.
The Journal of International Medical Research
|September 1, 1988
Summary
Elderly patients with chronic diseases effectively combat infections using ciprofloxacin. This antibiotic demonstrated high eradication rates and good tolerability in a study of older adults, highlighting its safety and efficacy.
Area of Science:
- Gerontology
- Infectious Diseases
- Pharmacology
Background:
- Advanced age and chronic diseases significantly increase infection susceptibility in elderly individuals.
- Comorbidities in the elderly can complicate infection management and reduce treatment efficacy.
Purpose of the Study:
- To evaluate the efficacy and safety of ciprofloxacin in treating infections in elderly patients.
- To assess the microbiological and clinical outcomes of ciprofloxacin therapy in a geriatric population.
Main Methods:
- A study involving 212 elderly patients (65-98 years) treated with ciprofloxacin (500-1000 mg/day) for 1-18 days.
- Microbiological and clinical assessments were performed to determine treatment success and failure rates.
- Adverse events and side-effects were monitored throughout the treatment period.
Main Results:
- Microbiological eradication of infections was achieved in 88.5% of patients.
- Clinical resolution of infection symptoms was observed in 75.5% of the study participants.
- Clinical failure was reported in only 6.1% of patients, with treatment generally well-tolerated.
Conclusions:
- Ciprofloxacin is an effective and safe antimicrobial option for treating infections in the elderly population.
- The antibiotic demonstrated a favorable safety profile, with minimal side-effects reported in this cohort.
- Despite the challenges posed by advanced age and comorbidities, ciprofloxacin achieved high success rates.