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Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
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Related Experiment Video

Updated: Dec 30, 2025

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Enabling Technologies for Personalized and Precision Medicine.

Dean Ho1, Stephen R Quake2, Edward R B McCabe3

  • 1The N.1 Institute for Health (N.1), National University of Singapore, Singapore; The Institute for Digital Medicine (WisDM), National University of Singapore, Singapore; Department of Biomedical Engineering, NUS Engineering, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Trends in Biotechnology
|January 26, 2020
PubMed
Summary
This summary is machine-generated.

Personalized medicine aims to tailor treatments by understanding complex health factors. Advances in enabling technologies are crucial for biomarker discovery and optimizing therapies for individual patient care.

Keywords:
artificial intelligenceclinical trialsdiagnosticspersonalized medicineprecision medicinetherapeutics

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Area of Science:

  • Biomedical engineering
  • Genomics
  • Proteomics

Background:

  • Individualized patient treatment is a key medical goal.
  • Complex genetic and protein factors influence disease and health, often remaining unknown.
  • Accurate diagnosis, monitoring, and treatment require better biomarker discovery and dynamic disease state signatures.

Purpose of the Study:

  • To highlight breakthroughs in enabling technologies for personalized and precision medicine.
  • To identify remaining challenges in achieving truly individualized patient care.

Main Methods:

  • Review of key technological advancements in biomarker discovery.
  • Analysis of strategies for developing dynamic disease signatures.
  • Exploration of methods for optimizing therapeutic interventions, including dose and drug selection.

Main Results:

  • Significant progress has been made in developing technologies that support personalized medicine.
  • Key breakthroughs facilitate the discovery of biomarkers and the development of disease signatures.
  • Enabling technologies are advancing the modulation of therapeutic interventions for individualized care.

Conclusions:

  • Technological advancements are critical for achieving personalized and precision medicine.
  • Addressing current challenges will unlock unprecedented capabilities in individualized patient care.
  • Continued innovation in enabling technologies is essential for the future of tailored medical treatments.