Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Re-Evaluating the Treatment Plan for Diabetic Macular Edema Based on Early Identification of Response and Possible Biochemical Predictors of Non-Response After the First Intravitreal Ranibizumab Injection.

Biomedicines·2025
Same author

The Astrocyte Elevated Gene- 1 Expression and other Risk Factors for Different Varieties of Diabetic Optic Neuropathy in Egyptian Patients with Diabetic Retinopathy.

Journal of molecular neuroscience : MN·2025
Same author

Assessment of retinal microvascular changes in patients with systemic lupus erythematosus using optical coherence tomography angiography.

International journal of retina and vitreous·2025
Same author

Comparing the success rate of external dacryocystorhinostomy with anterior flap versus flap excision in managing chronic dacryocystitis.

Medical hypothesis, discovery & innovation ophthalmology journal·2023
Same author

Efficacy of Topical Azithromycin versus Systemic Doxycycline in Treatment of Meibomian Gland Dysfunction.

Journal of ophthalmology·2023
Same author

Comparison between intravitreal ranibizumab injection and posterior subtenon triamcinolone acetonide injection at time of cataract surgery for prevention of progression of diabetic macular edema.

BMC ophthalmology·2022

Related Experiment Video

Updated: Dec 30, 2025

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy
07:12

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy

Published on: September 27, 2021

2.7K

Submacular perfluorocarbon liquid: long-term follow-up.

Hamouda Hamdy Ghoraba1,2, Hashem Hamouda Ghoraba1,2, Mohamed Amin Heikal3

  • 1Ophthalmology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.

International Ophthalmology
|January 26, 2020
PubMed
Summary

Retained submacular perfluorocarbon liquid (PFCL) bubbles occurred in nearly 1% of vitrectomy surgeries, often associated with large or post-equatorial retinal breaks. Long-term follow-up showed varied outcomes for these PFCL droplets.

Keywords:
PerfluorocarbonRetainedSubmacular

More Related Videos

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
07:13

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach

Published on: December 7, 2016

13.8K
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

4.2K

Related Experiment Videos

Last Updated: Dec 30, 2025

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy
07:12

Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy

Published on: September 27, 2021

2.7K
An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach
07:13

An Alternative and Validated Injection Method for Accessing the Subretinal Space via a Transcleral Posterior Approach

Published on: December 7, 2016

13.8K
Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

4.2K

Area of Science:

  • Ophthalmology
  • Retinal Surgery

Background:

  • Perfluorocarbon liquids (PFCLs) aid retinal reattachment during vitrectomy by displacing subretinal fluid.
  • Inadvertent retention of PFCL droplets in the submacular space can occur despite their benefits.

Purpose of the Study:

  • To evaluate the long-term outcomes of patients with retained submacular perfluorocarbon liquid (PFCL) after vitrectomy.
  • Identify risk factors and clinical course of submacular PFCL retention.

Main Methods:

  • Retrospective case series of 1224 vitrectomy patients.
  • Analysis of retained submacular PFCL cases, focusing on predisposing factors and outcomes.
  • Minimum follow-up of 18 months.

Main Results:

  • Submacular PFCL retention occurred in 0.98% of cases (12 eyes).
  • Risk factors included post-equatorial (50%) and large (25%) retinal breaks.
  • No significant difference in retention rates between perfluorodecalin and perfluoro-n-octane.

Conclusions:

  • Submacular PFCL migration is an infrequent complication of vitrectomy, primarily in complex retinal detachment cases.
  • Outcomes for retained submacular PFCL vary, with some small droplets maintaining fair visual acuity long-term.
  • Choice of PFCL (perfluorodecalin vs. perfluoro-n-octane) did not impact retention rates.