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Refractory palmoplantar pustulosis succesfully treated with apremilast
Raquel Carrascosa de Lome1, Elena Conde Montero1, Pablo de la Cueva Dobao1
1Dermatology Department, Hospital Universitario Infanta Leonor, Madrid, Spain.
Abstract:
Palmoplantar pustulosis is a chronic inflammatory disease which characterized by a eruption of sterile pustules on the palms and soles. Apremilast is an oral phosphodiesterase-4 inhibitor which is approved for the treatment of chronic plaque psoriasis and psoriatic arthritis. However, no clinical trial has been performed to confirm the efficacy of apremilast for palmoplantar pustulosis yet. Moreover, there are very few cases of this disease treated with apremilast. Herein, we describe a case of a refractory palmoplantar pustulosis succesfully treated with apremilast.

