Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Urodynamic Studies: Uroflowmetry01:19

Urodynamic Studies: Uroflowmetry

2.6K
Uroflowmetry is a non-invasive urodynamic test designed to measure various aspects of urination, including volume, flow rate, and the time to void. This test is crucial for diagnosing and assessing conditions such as bladder outlet obstruction, bladder dysfunction, incomplete bladder emptying, incontinence, and urinary tract blockages caused by benign prostatic hyperplasia (BPH) and urethral strictures.Pre-Test Instructions:Before a uroflowmetry test, patients are typically advised to drink...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic Value of Urine Sodium in Patients With Acute Decompensated Heart Failure: A Systematic Review and Meta-Analysis.

Cureus·2026
Same author

Cardio amyloid-artificial intelligence: advanced multi-modal screening for transthyretin cardiac amyloidosis in severe aortic stenosis patients.

European heart journal. Digital health·2026
Same author

An artificial intelligence model to detect abnormal ejection fraction from non-contrast chest computed tomography: the CT-LVEF study.

European heart journal. Digital health·2026
Same author

The novelty of anticoagulation in LVAD Therapy: Current Practice, the Role of Direct Oral Anticoagulants, and Future Directions.

Journal of cardiovascular pharmacology·2026
Same author

A two-threshold donor-derived cell-free DNA algorithm improves detection of molecular rejection in heart transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation·2026
Same author

De Novo Aortic Insufficiency and Its Progression in Patients on Microaxial Flow Pump Support Before Durable Left Ventricular Assist Device.

ASAIO journal (American Society for Artificial Internal Organs : 1992)·2026

Related Experiment Video

Updated: Dec 30, 2025

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
04:48

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery

Published on: November 28, 2018

8.2K

HVAD Flow Waveform Estimates Left Ventricular Filling Pressure.

Teruhiko Imamura1, Nikhil Narang2, Daniel Rodgers3

  • 1Department of Medicine, University of Chicago Medical Center, Chicago, Illinois; Second Department of Medicine, University of Toyama, Toyama, Japan.

Journal of Cardiac Failure
|January 26, 2020
PubMed
Summary

The ventricular filling phase slope (VFPS) from the HeartWare Ventricular Assist Device (HVAD) can estimate pulmonary capillary wedge pressure (PCWP). This noninvasive method accurately predicts PCWP and identifies patients at higher risk for heart failure readmission.

Keywords:
Heart failureheartwareventricular assist device

More Related Videos

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
11:04

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

11.5K
Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

6.9K

Related Experiment Videos

Last Updated: Dec 30, 2025

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery
04:48

Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery

Published on: November 28, 2018

8.2K
Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism
11:04

Quantification of Global Diastolic Function by Kinematic Modeling-based Analysis of Transmitral Flow via the Parametrized Diastolic Filling Formalism

Published on: September 1, 2014

11.5K
Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
09:20

Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction

Published on: February 13, 2021

6.9K

Area of Science:

  • Cardiovascular Engineering
  • Medical Devices
  • Hemodynamics

Background:

  • HeartWare Ventricular Assist Device (HVAD) flow waveforms offer real-time insights into device performance and hemodynamics.
  • Previous research indicated a correlation between the ventricular filling phase slope (VFPS) and pulmonary capillary wedge pressure (PCWP).

Purpose of the Study:

  • To validate the utility of VFPS for estimating PCWP.
  • To assess VFPS's ability to predict clinical outcomes in HVAD patients.

Main Methods:

  • A prospective, blinded study involving 131 simultaneous measurements from 27 HVAD patients.
  • VFPS was calculated from HVAD monitor screenshots by blinded reviewers.
  • Estimated PCWP derived from a validated equation was correlated with invasively measured PCWP.

Main Results:

  • A VFPS cutoff of ≥5.8 L/min/s demonstrated high accuracy (91.5% sensitivity, 95.2% specificity) in predicting PCWP ≥ 18 mmHg.
  • Estimated PCWP showed a significant correlation (R²=0.65, P<.001) and acceptable agreement with measured PCWP.
  • Patients with VFPS ≥ 5.8 L/min/s had significantly higher heart failure readmission rates (0.24 vs 0.05 events/y, P<.001).

Conclusions:

  • The VFPS derived from HVAD flow waveforms is a novel, noninvasive parameter for estimating PCWP.
  • This method can aid in monitoring hemodynamic status and identifying high-risk patients.