Follicular wave synchronization prior to ovum pick-up
Marcelo Marcondes Seneda1, Amanda Fonseca Zangirolamo1, Larissa Zamparone Bergamo2
1Universidade Estadual de Londrina, Laboratório de Reprodução Animal, DCV-CCA-UEL, Londrina, Parana, Brazil; National Institute of Science and Technology for Dairy Production Chain (INCT-LEITE), Universidade Estadual de Londrina, Rodovia Celso Garcia Cid-Campus Universitário, PO Box 10011, Londrina, Parana, 86057-970, Brazil.
Theriogenology
|January 27, 2020
Summary
Improving in vitro embryo production (IVEP) requires enhancing oocyte quality and ovum pick-up (OPU) efficiency. Strategies like follicular synchronization and targeted gonadotrophic stimulus can boost oocyte recovery and competence for better IVEP outcomes.
Area of Science:
- Reproductive Biotechnology
- Animal Science
- Veterinary Medicine
Background:
- In vitro embryo production (IVEP) is crucial for genetic advancement in livestock.
- Recent advancements in ovum pick-up (OPU) have increased in vitro embryo production significantly.
- IVEP rates have plateaued at 30-40%, necessitating improvements in oocyte quality and recovery.
Purpose of the Study:
- To review strategies for improving oocyte quality and quantity in ovum pick-up (OPU) procedures.
- To identify methods that enhance the efficiency and success rate of in vitro embryo production (IVEP).
- To address challenges hindering the widespread application of OPU/IVEP programs.
Main Methods:
- Review of existing literature on OPU/IVEP techniques and challenges.
- Exploration of methods to improve oocyte recovery and quality.
- Discussion of strategies including follicular wave synchronization, antral follicle population management, and pre-OPU stimulation.
Main Results:
- Oocyte quantity and quality are critical for successful IVEP.
- Follicular wave synchronization can optimize oocyte retrieval.
- Pre-OPU gonadotrophic stimulus and non-hormonal selection methods show promise for improving outcomes.
Conclusions:
- Optimizing OPU procedures through targeted strategies is essential for advancing IVEP.
- Implementing methods like follicular synchronization and selective donor selection can enhance oocyte competence.
- Further research into these alternatives can overcome IVEP plateaus and improve genetic multiplication efforts.
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