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A cost-effectiveness analysis after implementation of a fast-track protocol for total knee arthroplasty
Joris A Jansen1, Jeroen Kruidenier1, Bea Spek2
1Orthopedic Department, Alrijne Hospital, Leiden, the Netherlands.
The Knee
|January 27, 2020
Summary
Fast-track total knee arthroplasty (TKA) significantly reduces hospital stay and costs without compromising patient outcomes or quality of life. This cost-effective approach is safe, with low complication rates up to 12 months post-surgery.
Area of Science:
- Orthopedic surgery
- Health economics
- Patient outcomes research
Background:
- Fast-track protocols in arthroplasty aim to improve patient recovery and reduce hospital stays.
- Limited research exists on the long-term cost-effectiveness and quality of life impacts of fast-track total knee arthroplasty (TKA).
- This study addresses the need to evaluate fast-track TKA's effects on functional outcomes, costs, and quality of life up to 12 months postoperatively.
Purpose of the Study:
- To analyze the cost-effectiveness of fast-track TKA compared to non-fast-track protocols.
- To assess the impact of fast-track TKA on functional outcomes, length of stay, and thromboembolic complications.
- To evaluate health-related quality of life using Quality-Adjusted Life Years (QALYs) at 12 months post-surgery.
Main Methods:
- Retrospective cohort study comparing 403 fast-track TKA patients with 283 non-fast-track TKA patients.
- Data collected included postoperative length of stay, thromboembolic complications, and healthcare production costs.
- Quality of life was measured using EQ-5D questionnaires to derive QALY scores.
Main Results:
- No significant differences in functional outcome or quality of life were observed between the groups.
- Fast-track TKA reduced median length of stay from five days to three days.
- The fast-track protocol resulted in an average cost reduction of €268 per patient, with comparable QALY scores (0.85 vs. 0.84).
Conclusions:
- Fast-track TKA is a safe and cost-effective strategy, demonstrating high QALY and reduced medical costs.
- The protocol effectively shortens hospital stays without increasing the rate of thromboembolic complications.
- This study provides novel, long-term (12-month) data on the functional and quality-of-life benefits of fast-track TKA.

