Related Experiment Video
Updated: Dec 30, 2025
06:18
Measurement of Myocardial Lactate Production for Diagnosis of Coronary Microvascular Spasm
Published on: September 17, 2021
1.8K
Ductal arterial spasm: a nightmare
1Cardiac Medical Unit, Pediatric Department, Yankin Children Hospital, University of Medicine II, Yangon, Myanmar.
Cardiology in the Young
|January 28, 2020
Summary
Ductal spasm during patent ductus arteriosus (PDA) closure can be dangerous, potentially leading to incorrect device selection and severe complications. Early recognition is crucial to prevent adverse outcomes in this otherwise safe procedure.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Interventional Cardiology
Background:
- Percutaneous device closure is a standard, safe intervention for patent ductus arteriosus (PDA).
- Potential complications, though rare, necessitate careful procedural monitoring.
- Understanding anatomical variations and potential intra-procedural events is key.
Observation:
- Ductal arterial spasm occurred during transcatheter closure of PDA in two pediatric patients.
- This spasm was not recognized prior to device selection and deployment.
- The spasm significantly impacted the procedural course and device choice.
Findings:
- Unrecognized ductal spasm can mislead device selection for PDA closure.
- Failure to identify spasm can escalate to serious complications.
- In one reported case, ductal spasm during PDA closure led to patient mortality.
Implications:
- Highlights the critical importance of recognizing ductal spasm during PDA interventions.
- Emphasizes the need for vigilance and appropriate management strategies to mitigate spasm-related risks.
- Suggests potential modifications in procedural protocols to enhance safety in transcatheter PDA closure.
Related Concept Videos
01:16Vascular Spasm
3.1K
The vascular phase, also known as vasospasm, is the initial stage of hemostasis, crucial for preventing excessive bleeding when a blood vessel is injured. After a vessel is cut, nerves in the damaged area trigger pain and other sensory impulses. Simultaneously, the smooth muscles in the vessel wall contract, resulting in a vascular spasm. This contraction reduces the vessel's diameter at the injury site, slowing or stopping blood loss through the vessel wall. Vascular spasms typically last...
3.1K
01:21Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
279
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
279
01:30Aneurysm I: Introduction
222
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
222
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
152
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
152
01:22Aortic Regurgitation II: Clinical Features and Diagnostic Tests
317
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
317
01:27Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
388
Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...
388