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Estimation of Nephron Number in Whole Kidney using the Acid Maceration Method
Published on: May 22, 2019
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New imaging tools to measure nephron number in vivo: opportunities for developmental nephrology
K M Bennett1, E J Baldelomar1, D Morozov1
1Department of Radiology, Washington University, Saint Louis, MO, USA.
Journal of Developmental Origins of Health and Disease
|January 28, 2020
Abstract:
The mammalian kidney is a complex organ, requiring the concerted function of up to millions of nephrons. The number of nephrons is constant after nephrogenesis during development, and nephron loss over a life span can lead to susceptibility to acute or chronic kidney disease. New technologies are under development to count individual nephrons in the kidney in vivo. This review outlines these technologies and highlights their relevance to studies of human renal development and disease.

