Tuberculosis and Melioidosis at Distinct Sites Occurring Simultaneously
1Department of Infectious Diseases, Changi General Hospital, Singapore.
Case Reports in Infectious Diseases
|January 28, 2020
Summary
This report details a rare case of tuberculosis and melioidosis coinfection at distinct sites in a single patient. Early diagnosis and treatment of both infections are crucial for patient recovery.
Area of Science:
- Infectious Diseases
- Microbiology
- Clinical Medicine
Background:
- Tuberculosis (TB) and melioidosis are endemic in Southeast Asia.
- Coinfection with Mycobacterium tuberculosis and Burkholderia pseudomallei is exceptionally rare.
- This study presents a unique case of TB and melioidosis at noncontiguous sites.
Observation:
- A 64-year-old male with a history of alcohol abuse presented with abdominal pain, weight loss, and fever.
- Diagnostic workup revealed disseminated tuberculosis affecting pulmonary and gastrointestinal systems.
- A splenic abscess caused by melioidosis was also identified.
Findings:
- The patient received concurrent treatment for both tuberculosis and melioidosis.
- The treatment regimen addressed pulmonary and gastrointestinal TB, alongside the splenic abscess.
- Successful outcomes were achieved with symptom resolution and radiological clearance of the splenic abscess.
Implications:
- Melioidosis and tuberculosis share overlapping clinical presentations.
- Increased clinical and microbiological awareness is vital for diagnosing rare coinfections.
- Prompt diagnosis and management of coexisting TB and melioidosis are essential for favorable patient outcomes.
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