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Epidemiology and Management of Children with Hypertensive Crisis: A Single-Center Experience
Alicia May Lim1, Siew Le Chong1, Yong Hong Ng1
1Department of Paediatrics, KK Women's and Children's Hospital, Singapore, Singapore.
Insights
Pediatric hypertensive crisis is usually secondary to other conditions, most often renal pathology. Oral nifedipine and intravenous labetalol are effective treatments for children experiencing hypertensive crisis.
Area of Science:
- Pediatric Nephrology
- Cardiology
- Clinical Pediatrics
Background:
- Hypertensive crisis in children often indicates an underlying secondary cause.
- Understanding the epidemiology and management is crucial for pediatric care.
Purpose of the Study:
- To describe the epidemiology and management of pediatric hypertensive crisis.
- To identify common causes and effective treatments for hypertensive crisis in children.
Main Methods:
- Retrospective cohort study conducted in a tertiary pediatric hospital.
- Analysis of 37 patients treated for hypertensive crisis between 2009 and 2015.
Main Results:
- The majority of patients (89.1%) had secondary hypertension, with renal pathology being the most common cause (48.6%).
- Oral nifedipine (62.1%) and intravenous labetalol (21.6%) were the most frequently used antihypertensives.
- No mortalities or morbidities were reported.
Conclusions:
- Pediatric hypertensive crisis is predominantly secondary.
- Oral nifedipine and intravenous labetalol are effective and safe treatment options for pediatric hypertensive crisis.
Abstract:
Most children who present with hypertensive crisis have a secondary cause for hypertension. This study describes the epidemiology and management of children with hypertensive crisis. A retrospective cohort study was done in a tertiary pediatric hospital from 2009 to 2015. Thirty-seven patients were treated for hypertensive crisis. Twelve (32.4%) patients were treated for hypertensive emergency. The majority of our patients (33 [89.1%]) had a secondary cause of hypertension. The most common identifiable cause of hypertension was a renal pathology (18/37 [48.6%]). Oral nifedipine (23 [62.1%]) was the most frequently used antihypertensive, followed by intravenous labetalol (8 [21.6%]). There were no mortalities or morbidities. Hypertensive crisis in children is likely secondary in nature. Oral nifedipine and intravenous labetalol are both effective treatments.
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