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Refraction under general anesthesia in children, using cycloplegic refraction only as a reference
Osman Bulut Ocak1, Asli Inal1, Beril Tülü Aygün1
1Beyoglu Eye Training and Research Hospital, University of Health Sciences , Istanbul.
Insights
Pediatric refractive measurements under general anesthesia (GA) were more myopic than cycloplegic refraction. This highlights that GA does not achieve complete cycloplegia, impacting auto-refractometer (ARF) readings.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Refractive Error Assessment
Background:
- Accurate refractive error assessment is crucial for pediatric eye care.
- General anesthesia (GA) is sometimes necessary for pediatric eye examinations.
- The impact of GA on auto-refractometer (ARF) readings requires careful consideration.
Purpose of the Study:
- To compare pediatric refractive measurements obtained via auto-refractometer (ARF) under general anesthesia (GA) with those from cycloplegic refraction.
- To evaluate the agreement and correlation between these two measurement methods.
Main Methods:
- A study included 222 pediatric patients (36-60 months) undergoing ARF (Retinomax® K plus 3) under GA.
- Cycloplegic refraction using 1% cyclopentolate and the same ARF device was performed within 3 months prior to GA.
- Bland-Altman analysis and Pearson correlation were used to analyze measurement agreement and correlation.
Main Results:
- A strong positive correlation (r=0.95) was found between GA and cycloplegic refraction measurements.
- Refractive measurements under GA were significantly more myopic (-1.49 D) than cycloplegic refraction.
- Differences were within ±1 D in 41.44% and within ±2 D in 81.01% of eyes; no significant difference in cylindrical error.
Conclusions:
- Pediatric refractive measurements under GA tend to be more myopic compared to cycloplegic refraction.
- General anesthesia does not induce complete cycloplegia, influencing autorefractor readings.
- Clinicians should be aware of these differences when interpreting ARF data obtained under GA.
Purpose:
To compare the measurements of cycloplegic refraction and refraction (R1-1) under general anesthesia (GA) when using the same portable auto-refractometer (ARF) in pediatric patients.
Methods:
36Thirty-six to 60-month-old patients who underwent refraction measurements using a portable ARF (Retinomax® K plus 3, Righton, Japan), who did not receive prior cycloplegics under this GA and who had cycloplegic refraction using 1% cyclopentolate and the same Retinomax® device < 3 months prior this GA, between 2015 and 2018, were included in this study. The agreement (Bland-Altman analysis) and correlation (Pearson correlation) between the mean values of the measurements were analyzed.
Results:
Two-hundred-twenty-two right eyes of 222 patients (114 male and 108 female) were included in this study. The mean age was 45.04 ± 11.24 months. The mean spherical refractions (R1-1, R2-1) under GA and cycloplegic refraction were 1.08 ± 3.50 diopter (D) (-8.00 to +8.00) and 2.58 ± 3.28 D (-6.50 to +9.25), respectively. A strong positive correlation was detected between the two measurements (r = 0.95). When comparing measurements, the mean measurement under GA was -1.49 D (95% confidence interval: lower limit, -3.63; upper limit, +0.63) more myopic than the mean cycloplegic refraction (R1-1) value (Bland-Altman analysis test). The differences between the measurements were within ± 1 D in 92 eyes (41.44%) and within ± 2 D in 180 eyes (81.01%). No significant difference was detected when comparing the cylindrical refractive error values (p > .05).
Conclusion:
Refractive measurements under GA were more myopic than cycloplegic refraction (R1-1) measurements. It is important to consider that complete cycloplegia is not achieved under GA.
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