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Updated: Dec 30, 2025

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
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An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

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Non-Rheumatic Mitral Annular Calcification as a Cause of Late-Onset Mitral Stenosis

Chirag K Desai1, Jon Orvarsson2, Adam Stys1

  • 1Division of Cardiovascular Disease, University of South Dakota Sanford School of Medicine School of Medicine, Sioux Falls, South Dakota.

South Dakota Medicine : the Journal of the South Dakota State Medical Association
|January 28, 2020
PubMed

Insights

Senile calcific mitral stenosis, though rare, presents unique treatment challenges. Surgical bioprosthetic valve replacement effectively managed a patient with severe symptomatic mitral stenosis.

Area of Science:

  • Cardiology
  • Valvular Heart Disease
  • Geriatric Cardiology

Background:

  • Rheumatic heart disease is the primary global cause of mitral stenosis.
  • Senile calcific mitral stenosis is increasingly recognized, particularly in developed countries.
  • This condition involves degenerative changes in the mitral valve leaflets.

Observation:

  • The case involved a patient with symptomatic severe mitral stenosis.
  • The underlying cause was identified as senile calcific mitral stenosis.
  • Treatment options for this specific type of stenosis are often limited.

Findings:

  • Surgical bioprosthetic valve replacement was chosen as the management strategy.
  • The procedure addressed the severe mitral stenosis effectively.
  • This highlights a viable surgical option for complex cases.

Implications:

  • Surgical valve replacement offers a solution for severe senile calcific mitral stenosis.
  • Further research into less invasive options may be warranted.
  • Improved understanding of senile calcific mitral stenosis can guide clinical practice.

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