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Updated: Dec 30, 2025

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Outcomes of non-elective coronary artery bypass grafting performed on weekends
Jared P Beller1, William Z Chancellor1, J Hunter Mehaffey1
1Division of Cardiac Surgery, Department of Surgery, University of Virginia, Charlottesville, VA, USA.
Insights
Weekend surgery for coronary artery bypass grafting (CABG) did not increase patient mortality. However, patients undergoing weekend CABG faced higher risks of major morbidity, warranting further investigation into the causes.
Area of Science:
- Cardiovascular Surgery
- Health Services Research
- Surgical Outcomes
Background:
- A
- weekend effect
- has been observed in surgical patients and those with acute myocardial infarction (MI), suggesting increased mortality.
- The existence of a similar phenomenon in coronary artery bypass grafting (CABG) procedures was hypothesized.
Purpose of the Study:
- To investigate whether a
- weekend effect
- impacts mortality and morbidity in patients undergoing non-elective isolated CABG.
Main Methods:
- Analysis of a multicentre regional Society of Thoracic Surgeons database for non-elective isolated CABG patients from 2011-2017.
- Patients were stratified into weekend versus weekday operation groups and analyzed by specific day of the week.
- Risk-adjusted analyses were performed to assess the impact of weekend surgery on mortality and morbidity.
Main Results:
- Weekend CABG operations were more likely to be emergencies and associated with MI (70.0% vs 51.2%).
- Risk-adjusted analyses showed no increased odds of mortality for weekend CABG (OR 1.07, P=0.811).
- A significant increase in major morbidity was observed for weekend operations (OR 1.37, P=0.034), with morbidity increasing from Tuesday through the weekend.
Conclusions:
- There is no independent effect of weekend surgery on mortality for CABG patients, despite higher baseline risk.
- Patients undergoing weekend CABG face an elevated risk of major morbidity.
- The underlying causes for increased weekend morbidity require further investigation.
Objectives:
A weekend effect with increased mortality has previously been reported in surgical patients and those with acute myocardial infarction (MI). We hypothesized that a similar phenomenon may exist in coronary artery bypass grafting (CABG).
Methods:
Patients undergoing non-elective isolated CABG (2011-2017) were included from a multicentre regional Society of Thoracic Surgeons database. Patients were stratified by weekend versus weekday operations and further analysed by specific day of the week.
Results:
A total of 14 374 patients underwent urgent or emergency isolated CABG with 410 (2.9%) operated on over the weekend. Weekend operations were more often emergency (36.1% vs 5.0%, P < 0.001) and more likely to be in the setting of MI (70.0% vs 51.2%, P < 0.001). Cardiopulmonary bypass times were similar [91 min (71-114) vs 94 min (74-117), P = 0.0749] and the frequency of complete revascularization equivalent (83.4% vs 85.3%, P = 0.284) between weekend and weekday operations. In risk-adjusted analyses, there was no increased odds for mortality in patients operated on over the weekend [odds ratio (OR) 1.07, P = 0.811]; however, there was an increased odds of major morbidity (OR 1.37, P = 0.034). Furthermore, compared with Monday, morbidity increased as the operative day approached the weekend (Tuesday 0.98, P = 0.828; Wednesday 1.07, P = 0.469; Thursday 1.12, P = 0.229; Friday 1.19, P = 0.041; weekend 1.47, P = 0.014).
Conclusions:
While patients requiring surgery on the weekend are higher risk, there is no independent effect of weekend surgery on mortality. However, these patients are at increased risk for major morbidity, the causes of which require further investigation.
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