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Assessment of Stress Effects on Cognitive Flexibility using an Operant Strategy Shifting Paradigm
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Stress and neurodegeneration.

Carmen Peña-Bautista1, Esther Casas-Fernández1, Máximo Vento1

  • 1Health Research Institute La Fe, Valencia, Spain.

Clinica Chimica Acta; International Journal of Clinical Chemistry
|January 29, 2020
PubMed
Summary

Chronic stress accelerates neurodegenerative diseases like Alzheimer's and Parkinson's. Stress reduction therapies show promise, but further research is needed to understand their full impact on neurodegeneration.

Keywords:
NeurodegenerationNeurodegenerative diseaseStress

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Area of Science:

  • Neuroscience
  • Pathology
  • Gerontology

Background:

  • Aging populations worldwide increase concern over neurodegenerative diseases.
  • The complex etiology of neurodegeneration remains incompletely understood.
  • Chronic stress is increasingly implicated in neurodegenerative pathology.

Purpose of the Study:

  • To review the influence of stress on neurodegeneration.
  • To examine the impact of neurodegenerative disease diagnosis on patient stress levels.
  • To evaluate therapeutic strategies for neurodegenerative diseases, focusing on stress reduction.

Main Methods:

  • Literature review of studies on stress and neurodegeneration.
  • Analysis of the effects of stress on Alzheimer's, Parkinson's, and Huntington's disease.
  • Evaluation of stress-reduction therapies for neurodegenerative conditions.

Main Results:

  • Stress accelerates disease progression and worsens symptoms in neurodegenerative disorders.
  • Neurodegenerative disease diagnosis can significantly increase psychological stress.
  • Therapies like yoga and meditation demonstrate potential benefits in combating neurodegeneration.

Conclusions:

  • Stress is a significant factor exacerbating neurodegenerative diseases.
  • Stress reduction techniques may offer a valuable complementary approach to managing neurodegeneration.
  • Further research is essential to elucidate the precise role of stress and the efficacy of stress-reduction interventions in neurodegenerative disease treatment.