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The Epidemiology of Guillain-Barré Syndrome in Children under 15 Years Old in Southwest Iran

Ali Akbar Momen1, Abdolhussein Shakurnia2

  • 1Department of Pediatrics, Faculty of Medicine, Golestan Hospital, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Biomedicine Hub
|January 29, 2020
PubMed

Insights

The incidence of Guillain-Barré syndrome (GBS) in children under 15 in Southwest Iran was 1.51 per 100,000 annually. GBS occurrence peaked in autumn, with no significant sex-based difference in incidence.

Area of Science:

  • Neurology
  • Epidemiology
  • Pediatrics

Background:

  • Guillain-Barré syndrome (GBS) is a leading cause of acute flaccid paralysis.
  • Understanding GBS incidence is crucial for identifying risk factors.

Purpose of the Study:

  • To determine the incidence and epidemiological characteristics of GBS in children in Southwest Iran.
  • To analyze the annual time trends of GBS occurrence.

Main Methods:

  • Retrospective study from January 2006 to December 2015.
  • Data extracted from the national Acute Flaccid Paralysis Surveillance System database.

Main Results:

  • 184 pediatric GBS cases were assessed.
  • The average annual incidence rate was 1.51 per 100,000 children (<15 years).
  • GBS incidence showed seasonal variation, peaking in autumn (32.2%) and lowest in summer (14.7%).

Conclusions:

  • The annual GBS incidence in this cohort is comparable to other regional studies.
  • Findings contribute to understanding GBS epidemiology in pediatric populations.
Abstract

Keywords:
ChildrenEpidemiologyGuillain-Barré syndromeIran

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