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Changes in the brainstem evoked responses following jugular vein ligation
1Department of Otorhinolaryngology, University of Liverpool.
The Journal of Laryngology and Otology
|October 1, 1988
Summary
Jugular vein ligation can cause intracranial hypertension. Brainstem evoked responses (BSER) detected brainstem compression after jugular vein ligation in guinea pigs, suggesting BSER monitoring for head and neck surgery.
Area of Science:
- Neuroscience
- Surgical Research
- Auditory Evoked Potentials
Background:
- Jugular vein blockage is associated with increased intracranial pressure.
- Early detection of brainstem compression is crucial in head and neck surgery.
Purpose of the Study:
- To investigate the utility of brainstem evoked responses (BSER) in detecting brainstem compression.
- To assess the effects of jugular vein ligation on BSER in a guinea pig model.
Main Methods:
- Thirty guinea pigs were divided into three groups: unilateral jugular vein ligation, bilateral jugular vein ligation, and control.
- Brainstem evoked responses (BSER) were recorded before and 6 hours after ligation.
- Hearing thresholds and interpeak intervals (I-III, III-IV) were analyzed.
Main Results:
- No significant changes in hearing thresholds were observed post-ligation.
- Prolongation of I-III and III-IV interpeak intervals was noted following both unilateral and bilateral jugular vein ligation.
- These findings indicate subclinical brainstem compression.
Conclusions:
- Brainstem evoked responses (BSER) show potential for early detection of brainstem compression.
- BSER monitoring may be a valuable tool during and after head and neck surgeries involving jugular vein manipulation.