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Isolation, Transfection, and Culture of Primary Human Monocytes
Published on: December 16, 2019
Cancer during HIV infection
Marinho Marques da Silva Neto1,2, Carlos Brites3, Álvaro H Borges4
1Department of Life Sciences, Bahia State University, Salvador, Bahia, Brazil.
Abstract:
HIV+ persons have a significantly increased risk of cancer when compared to the general population. The excess cancer risk observed during HIV infection is particularly higher for infection-related malignancies. Mechanisms underlying this remain unclear, but both HIV-related and HIV-unrelated factors have been postulated to play a role. Here, we (i) review newly published data on cancer burden in the setting of HIV infection with a focus on HIV-related risk factors for cancer; (ii) discuss emerging data on cancer among HIV+ persons living in low- and middle-income countries; and (iii) review guideline recommendations for cancer screening among HIV+ persons and discuss ongoing studies investigating strategies for cancer screening among HIV+ patients.
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