Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Artificial intelligence in contrast-induced nephropathy after coronary interventions: A meta-analysis.

Medicine·2026
Same author

Extracellular vesicles from glycolytic mesenchymal stromal cells restrain arthritis progression via IL-10-Producing T and B cells.

Theranostics·2026
Same author

Hemiptera diversity using the mtDNA COI barcode in almond orchards in the Northern San Joaquin Valley of California.

Journal of economic entomology·2026
Same author

Nanobubble-Mediated Oxygen Delivery Mitigates Hypoxia-Induced ROS and HIF-1α Expression in UC-MSCs.

Nanomaterials (Basel, Switzerland)·2026
Same author

Fate and function of exogenously administered mesenchymal stromal cells: current insights and future directions.

Cytotherapy·2025
Same author

Correction: A novel brain-to-gut communication pathway mediated by astrocyte-derived small extracellular vesicles modulates stress-induced intestinal inflammation.

Molecular psychiatry·2025
Same journal

Microfluidic rare cell analysis beyond counting: workflow design from enrichment to multi-omics.

Lab on a chip·2026
Same journal

A sperm racetrack to separate sperm by swim speed.

Lab on a chip·2026
Same journal

Controlled encapsulation and droplet size prediction in two-step microfluidic double emulsions.

Lab on a chip·2026
Same journal

A particulate blood-mimicking fluid with physiological biconcave geometry for microscale hemorheology.

Lab on a chip·2026
Same journal

Multicellular sensor arrays fabricated by capillary stamping for pattern-based odor discrimination.

Lab on a chip·2026
Same journal

A real-time microfluidic surveillance system for multiplex detection of heavy metal contamination in wastewater.

Lab on a chip·2026
See all related articles

Related Experiment Video

Updated: Dec 29, 2025

Assessing Neural Stem Cell Motility Using an Agarose Gel-based Microfluidic Device
12:55

Assessing Neural Stem Cell Motility Using an Agarose Gel-based Microfluidic Device

Published on: February 11, 2008

12.1K

Single cell migration profiling on a microenvironmentally tunable hydrogel microstructure device that enables stem

Enrique Ros1, Matías Encina1, Fabián González1

  • 1Cells for Cells, Santiago, Chile and Consorcio Regenero, Chilean Consortium for Regenerative Medicine, Santiago, Chile.

Lab on a Chip
|January 29, 2020
PubMed
Summary
This summary is machine-generated.

This study introduces a new microfluidic device using methacrylamide gelatin (GelMA) hydrogels for rapid cell migration analysis. The technology enables precise profiling of cell movement, aiding drug discovery and cell therapy development.

More Related Videos

Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging
09:36

Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging

Published on: December 23, 2011

25.7K
Single Cell Durotaxis Assay for Assessing Mechanical Control of Cellular Movement and Related Signaling Events
08:30

Single Cell Durotaxis Assay for Assessing Mechanical Control of Cellular Movement and Related Signaling Events

Published on: August 27, 2019

8.3K

Related Experiment Videos

Last Updated: Dec 29, 2025

Assessing Neural Stem Cell Motility Using an Agarose Gel-based Microfluidic Device
12:55

Assessing Neural Stem Cell Motility Using an Agarose Gel-based Microfluidic Device

Published on: February 11, 2008

12.1K
Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging
09:36

Evaluation of Cancer Stem Cell Migration Using Compartmentalizing Microfluidic Devices and Live Cell Imaging

Published on: December 23, 2011

25.7K
Single Cell Durotaxis Assay for Assessing Mechanical Control of Cellular Movement and Related Signaling Events
08:30

Single Cell Durotaxis Assay for Assessing Mechanical Control of Cellular Movement and Related Signaling Events

Published on: August 27, 2019

8.3K

Area of Science:

  • Biomaterials Engineering
  • Cell Biology
  • Microfluidics

Background:

  • Cell migration is crucial for physiological processes and diseases.
  • Accurate profiling of cell migration is vital for research and therapeutic applications.
  • Existing methods for analyzing cell migration can be limited in sensitivity and versatility.

Purpose of the Study:

  • To develop a novel microfluidic device for enhanced cell migration analysis.
  • To utilize methacrylamide gelatin (GelMA) hydrogels for creating microenvironments with encapsulated stimuli.
  • To enable quick, quantitative evaluation of cell migration behavior.

Main Methods:

  • Microfabrication of migration lanes using GelMA hydrogels.
  • Encapsulation of migration stimuli within the hydrogel matrix.
  • Development of a 3D topography device for cell localization.
  • Automated microscopy processing using an ImageJ plugin for quantification.

Main Results:

  • The GelMA-based device provides structural stability and tailored microenvironments.
  • The device allows for quick evaluation and quantification of individual cell migration distances.
  • The new assay demonstrates broader sensitivity and higher versatility compared to existing methods.
  • Parametric data from migration profiling were used to develop predictive models for immunosuppressive cell function.

Conclusions:

  • The developed microfluidic device offers a sensitive and versatile platform for cell migration studies.
  • This technology facilitates the development of predictive models for cell function, applicable to potency testing.
  • The findings support the advancement of drug discovery, cell therapy, and fundamental migration research.