Impulse oscillometry reference values and correlation with predictors in Turkish preschool children

Area of Science:

• Pediatric Pulmonology
• Respiratory Physiology
• Biostatistics

Background:

• Impulse oscillometry (IOS) is a noninvasive lung function test.
• No established IOS reference values exist for Turkish children.
• Accurate reference values are vital for diagnosing pediatric respiratory conditions.

Purpose of the Study:

• Determine IOS reference values for healthy Turkish preschool children.
• Investigate correlations between IOS parameters and anthropometric predictors (height, weight, BMI, age).
• Provide a normative dataset for clinical application in Turkey.

Main Methods:

• Recruited 151 healthy Turkish preschool children (3-7 years).
• Performed IOS to measure airway resistance and reactance (R5-R20, X5-X20), impedance (Z5), resistance area (AX), and resonance frequency (Fres).
• Utilized regression analysis and stepwise methods to assess correlations with anthropometric data.

Main Results:

• Established reference values for IOS parameters in Turkish preschool children.
• Found significant correlations: resistance with height, reactance with age.
• Identified sex-specific correlations between anthropometrics and IOS parameters.

Conclusions:

• This study provides the first reference values for IOS in Turkish preschool children.
• Height and age are significant predictors of IOS parameters in this population.
• These reference values will aid in diagnosing and monitoring respiratory diseases in young children.