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Related Experiment Video

Updated: Dec 29, 2025

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Sickle cell disease: A primary care update.

Grace Onimoe1, Seth Rotz2

  • 1Department of Pediatrics, The Metrohealth Hospital, and Assistant Professor, Case Western Reserve University, Cleveland, OH.

Cleveland Clinic Journal of Medicine
|January 29, 2020
PubMed
Summary

Sickle cell disease (SCD) management requires primary care physician involvement for adult health maintenance. This review outlines key recommendations, complications, and updates for managing SCD.

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Area of Science:

  • Hematology
  • Internal Medicine
  • Public Health

Background:

  • Sickle cell disease (SCD) is a prevalent hemoglobinopathy in the U.S.
  • SCD causes severe morbidity, including organ damage, anemia, and pain crises.
  • Adult patients with SCD require ongoing medical home care.

Purpose of the Study:

  • To review current health maintenance recommendations for adults with SCD.
  • To summarize SCD complications and recent therapeutic updates.
  • To guide primary care physicians in managing SCD.

Main Methods:

  • Literature review of current guidelines and research.
  • Synthesis of information on SCD complications.
  • Summary of recent advancements in SCD care.

Main Results:

  • Established health maintenance protocols are crucial for SCD patients.
  • Understanding SCD complications aids in proactive management.
  • Recent updates offer improved therapeutic options.

Conclusions:

  • Primary care physicians are vital in the medical home model for SCD.
  • Adherence to health maintenance guidelines can mitigate SCD morbidity.
  • Ongoing education on SCD complications and treatments is essential for optimal patient outcomes.