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The Gβ1 and Gβ3 Subunits Differentially Regulate Rat Vascular Kv7 Channels

Iain A Greenwood1, Jennifer B Stott1

  • 1Vascular Biology Research Centre, Institute of Molecular and Clinical Sciences, St George's University of London, London, United Kingdom.

Frontiers in Physiology
|January 30, 2020
PubMed
Summary

G-protein beta subunits Gβ1 and Gβ3 differentially regulate Kv7 potassium channels. Gβ1 impacts Kv7.4 protein levels, while Gβ3 controls basal vascular tone via Kv7 channels.

Keywords:
G protein signalingG protein βγ subunitsKv7 channelspotassium channelvascular smooth muscle

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