Related Experiment Video
Updated: Dec 29, 2025

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
[The power exercises as a risk factor of Parkinson's disease]
O V Guseva1, N G Zhukova1, I A Zhukova1
1Siberian State Medical University, Tomsk, Russia.
Aim:
To study the relationship between the physical condition, degree of motor disturbances and power loading in former athletes with Parkinson's disease (PD).
Material And Methods:
The study included 20 men with PD, including 10 power athletes with training loads in the youth for more than 5 years and 10 non-athletic patients. A medical history of PD and accompanied hypertension were analyzed, body mass index and power hand index were measured and the orthostatic test from supine to sitting position was made. Motor function was assessed with the unified Parkinson's disease rating scale of the Movement Disorder Society (MDS UPDRS) - part III.
Results And Conclusion:
Former athletes with PD were younger compared to non-athletic patients (57.44±8,14 vs. 66.78±4.29 years; p<005) and had longer duration of the disease (6.56±5,36 vs. 3.60±3.50 years; p<0.05). The orthostatic reaction of the former athletes was accompanied by increasing of diastolic blood pressure (DBP), while there was a decrease in DBD in the non-athletic men. Hypokinetic syndrome was more pronounced in the former athletes. The slowing of movements (bradykinesia) were accessed as 3 points on MDS UPDRS in 6 people and 4 points in 4. The results show the impact of power training on the course and presentations of PD in former athletes.
Related Concept Videos
Parkinson's Disease: Overview
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Neural Regulation
Peripheral Artery Disease I: Introduction

